Studies upon hypersusceptibility and immunity / by M.J. Rosenau and John F. Anderson.

  • Milton Rosenau
Date:
1907
Catalogue details

Licence: In copyright

Credit: Studies upon hypersusceptibility and immunity / by M.J. Rosenau and John F. Anderson. Source: Wellcome Collection.

    53/76 (page 51)
    Male (G. P. No. 4530). June 8, 1906. Immune. Placed in cage with above female. Previous treatment: January 12, 1906. 0.19 c. c. toxine 7 + 1 unit antitoxic horse serum (B27). January 22, 1906. Six c. c. antitoxic liorse serum (Natl. VIII, 17) intraperi- toneally. Definite symptoms. February 6, 1906. Ditto. February 8, 1906. February 14, 1906. February 23, 1906. March 25, 1906. April 18, 1906. Symptoms. No symptoms. No symptoms. No symptoms. Ditto (Natl. YIII, 18). No symptoms. Ditto. Ditto. No symptoms. Ditto. Ditto. Ditto. May 16, 1906. Six c. c. normal horse (roan) serum intraperitoneally. No symptoms. May 18 to June 27, 1906. One c. c. same serum subcutaneously daily (except Sunday), 22 injections. No symptoms. January 25, 1907. Six c. c. normal horse serum (horse No. 15). Very slight symptoms. Offspring, first litter. One young born December 26,1906. As soon as born, placed to nurse with untreated female (pen 120), whose young were placed to nurse with G. P. No. 4426. (G. P. No. 4426a.) January 25, 1907. Two c. c. normal horse (No. 15) serum intraperitoneally, when 30 days old. No symptoms. Young of untreated female P. 120. (G. P. No. P. 120a.) January 25, 1907. 35 days old. Two c. c. normal horse (No. 15) serum intraperitoneally. No symptoms. February 18,1907. 24 days later. Six c. c. same serum. Very severe symptoms. (G. P. No. P. 120b.) January 25, 1907. Same as G. P. No .P. 120a. No. symptoms. February 18, 1907. Ditto. Dead, 70 minutes. Second litter. Three young born March 1, 1907, and not exchanged. (G. P. No. 4426b.) March 26, 1907. 25 days old. Two c. c. normal horse (roan) serum intraperitoneally. No symptoms. (G. P. No. 4426c.) Same treatment. No symptoms. (G. P. No. 4426d.) Same treatment. No symptoms. These three pigs were again tested April 18 with 4 c. c. of normal hor.se (roan) serum into the peritoneal cavity. All three showed slight symptoms, thus proving that immunit}', or “ antianaphylaxis,” was not transmitted from the mother. FAMILY NO. 10. (Immune female; immune male. Exchange.) Female (G. P. No. 429). January 25, 1907. Sixc. c. normal horse (No. 15) serum intraperitoneally. Slight symptoms. [Previous treatment: May 18 to June 27, 1906, 1 c. c. normal horse (roan) serum daily except Sunday, 22 injections.] Male (G. P. No. 4530). June 8, 1906. Placed in cage with female. For history of this male, see Family No. 14.