Studies upon hypersusceptibility and immunity / by M.J. Rosenau and John F. Anderson.

  • Milton Rosenau
Date:
1907
Catalogue details

Licence: In copyright

Credit: Studies upon hypersusceptibility and immunity / by M.J. Rosenau and John F. Anderson. Source: Wellcome Collection.

    55/76 (page 53)
    FAMILY NO. 13. 1. (Iiuinune female; untreated male.) Female (G. P. No. 110). February 8 to 20, 1900. One c. c. Daily subcutaueous injections 1 c. c. antitoxic horse serum (Natl. IX, 19). No symptoms. March 29, 1900. Six c. c. antitoxic horse serum (Natl. VIII, 18). Mild symp- toms. April 4 to 17, 1900. One c. c. daily injections antitoxic horse serum (Natl. IX, 17). No symptoms. April 23, 1900. Six c. c. normal horse (roan) serum. Very slight symptoms. May 15, 1900. Ditto. Very slight symptoms. May 18 to June 27, 1900. One c. c. daily, same serum. No symptoms. September 7, 1900. Six c. c. normal horse (roan) serum, intraperitoneally. Very slight symptoms. Male (G. P. No. —). June 8, 1900. Untreated. Put in cage after immunization of female was well advanced. Oftspring. August 10, 1900. One young born, and tested as follows: (G. P. No. 110a.) September 7,1900. 27 days old. Two o. c. normal horse (roan) serum intraperitoneally. Very slight symptoms. FAMILY NO. 14. (Immune female; untreated male.) Female (G. P. No. 426). September 7, 1906. Six c. c. normal horse (roan) serum, intraperitoneally. Slight symptoms. [Previous treatment: May 19 to June 27, 1906, 1 c. c. daily subcutaneous injec- tions of normal horse (roan) serum.] Male (G. P. No. 426m). June 8, 1906. Untreated. Put in cage during period of immunization of female. Offspring. July 24, 1906. Two young born, and tested as follows: (G. P. ISo. 426a.) September 7, 1906. 41 days old. Two c. c. normal horse (roan) serum, intraperitoneally. Slight symptoms. (G. P. No. 426b.) Ditto. Slight symptoms. FAMILY NO. 15. (Immune female; untreated male. Exchange.) Female (G. P. No. 427). February 27, 1907. Six c. c. normal horse (roan) serum intraperitoneally. Severe symptoms. [Previous treatment: 245 days prior (May 18-to June 26) 1 c. c. normal horse (roan) serum subcutaneously daily.] No symptoms. Male (G. P. No. 42601). June 8, 1906. Normal. Put into cage during period of immunization of female. Offspring. January 22, 1907. Two young born. At once placed to nurse with untreated female. Tested as follows: (G. P. No. 427a.) February 27, 1907. 36 days old. Three c. c. normal horse (roan) serum intraperitoneally. Severe symptoms. (G. P. No. 427b.) Ditto. Dead, 62 minutes. Two young born of untreated female, but nursed with above female No. 427, tested as follows: (G. P. No. P. 108a.) February 27, 1907. 36 days old. Three c. c. normal horse (roan) serum intraperitoneally. No symptoms. (G. P. No. P. 108b.) Ditto. No symptoms.