Scientific reports on antipyrin : collected from the principal medical publications of the world / [Dr. Knorr].
- Date:
- 1890
Licence: Public Domain Mark
Credit: Scientific reports on antipyrin : collected from the principal medical publications of the world / [Dr. Knorr]. Source: Wellcome Collection.
Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.
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![even then its use was prolonged for a few days, twice 30 grains (6 Tabloids) being given dail}'. • From the Medical Policlinic in Erlangen—Anti- PYiUN, in fevers of children. By Prof. Dr. Penzoldt and E. Sar- TORius [Berlin klin., Wochcnschrift, 1884, N. 30). The authors used Antipyrin largely in children's affections. They prescribed it on 120 days to 21 little patients, and came to the follow^ing conclusions :— 1. Antipyrin given in febrile disorders of children is a very appropriate medication, which infallibly reduces the temperature. 2. Giveii in suitable doses it causes an abatement of several degrees, lasting for several hoiirs. 3. The decrease of the frequency of the pulse does not always correspond to the reduction of the temperature. 4. The effect on the patient's general conditions is mostly favourable. 5. In undesirable secondary effects vomiting was sometimes noticed. If this should occur frequently the drug had better be given per rectum. 6. Twice as many grains as the child counts years are given as a single dose, which is repeated three times, one hour intervening between each dose. Even larger doses may be given with perfect safety if the desired effect should not have been obtained. The appropriate dose for ad- ministration per rectum is: 5—10 times as many grains as the child is old. 7. The infantile organism seemed to adapt itself to the pro- longed introduction of the drug. From the Internal Clinic of Prof. Riegel in Giessen. —On the action of Antipyrin. By Carl v. Noorden, assistant ■of the Clinic (Berlin klin., Wochenschrift, 1884, N. 32). Antipyrin was exactly prescribed according to the rules laid down by Filehne (30 + 30 + 15 grains [6+6 + 3 Tabloids] with one](https://iiif.wellcomecollection.org/image/b21455375_0016.jp2/full/800%2C/0/default.jpg)


