Contributions to the physiology of lymph secretion / by Ernest H. Starling.

  • Ernest Starling
Date:
[1893]
Catalogue details

Licence: Public Domain Mark

Credit: Contributions to the physiology of lymph secretion / by Ernest H. Starling. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    second dog, B. A cannula was placed in the thoracic duct of B, and the blood-pressure of B was registered by means of a Hurthle’s manometer, connected with a femoral artery. Experiment 1. April 26th, 1892. Dog A weighs 8,000 grins. Dog B 7,000 grins. Lymph from B in every 10 minutes from 10.32 to 11.35 a.m.:— 4 c.c. 4 c.c. 3-25 c.e. 2’5 e.c. From 11.42 to 11.52 blood allowed to flow from A into B, the artery being held between the finger and thumb, so that the flow of blood could be accurately controlled. Care was taken not to let the transfusion take place too rapidly, only small amounts of blood being allowed to flow in at a time, by releasing the compression on the artery for a second and then closing it again. The blood-pressure in B rose slightly. By comparing the weight of A before and after experiment, it was calculated that 350 grins, had been transfused. Lymph in every 10 minutes after transfusion from 11.52 to 12.32 :— 5 c.c. 5 c.c. 4-5 c.c. 4-5 c.c. Experiment 2. June ls£, 1892. A weighs before transfusion 5510 grins. A weighs after „ 5260 ,, The amount of blood transfused therefore = 250 grins. B weighs 12-450 grs. Lymph from B in each 10 min. from 10.40 to 11 a.m.:— 6 c.c. 5 c.c. From 11 to 11.9 blood allowed to flow from A into B. Blood-pressure in B rose considerably. Lymph from B in every 10 min. from 11.10 to 11.40 :— 8-5 c.c. 9 c.c. 10 c.c. 2. Effect of transfusing defibrinated blood. In Experiment 2, at 11.45 a.m. the dog B was bled to 220 c.c. The blood was whipped and strained. The effect of the bleeding was to cause a slight decrease in the lymph. Thus in each 10 min. from 11.47 to 12.7, the lymph amounts were:— 7'5 c.c. 5 c.c. From 12.8 to 12.18 p.m., the defibrinated blood was allowed to flow ui again by the facial vein.
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