Volume 1
The extra pharmacopœia of Martindale and Westcott.
- William Martindale
- Date:
- 1920-1921
Licence: Public Domain Mark
Credit: The extra pharmacopœia of Martindale and Westcott. Source: Wellcome Collection.
21/1212
![]“ Effects of Excessive Dose,” “ Clinical Experience ” and “ General j References.” Protein Therapy.—An attempt has been made to systematise this somewhat discursive matter for convenience in ready reference. We commence with an account of Skin Reactions, giving details as to the manufacture of the Test Solutions, then follow directions as to technique in application of tests, and remarks on diagnostic i value. Subsequently, the subject of Peptone Immunisation in 1 bronchial asthma, with directions for its conduct, is dealt with. The treatment has been used in a variety of conditions, exhibiting an anaphylactic character or sensitisation. At the conclusion of these remarks is a note on Milk Injections in gonorrhoea, with the raison d'etre, of the method. Coming now to more defined bodies, in the Phenolphtlialein chapter will be found ample details of Flumerin and Mercuro- chrome “ 220.” The former is a new mercurial for intravenous treatment of syphilis, and the last-mentioned a vesical antiseptic containing over 20% of Mercury. As a general rule, 1% solutions of Mercurochrome are used as bladder irrigants. The recom¬ mendation to employ 25% solutions in gonorrhoea requires careful thought, and further experimental knowledge. Oleum TerGbmtilines.—In certain types of skin affections, winch are detailed, intramuscular injections of Rectified Turpentine in Olive Oil have proved beneficial. Potassium Iodide.—There is, under this heading, some useful advice on the treatment of goitre. Switzerland has been attacking the problem of its lack of Iodine in the water in the Alpine Valleys by adding Potassium Iodide, in small proportion to table water. (See also Therapeutic Index and Sodium Iodide.) With regard to exophthalmic goitre (see p. 699) small doses of Sodium Iodide given in the spring and autumn have reduced the number of cases in the districts where it is endemic, and the reasonable expectation is that by reducing tendency to simple goitre in early life the number of cases of Graves’ disease, occurring in later life, may also be lessened. Quinidine, Cinchonidine, Cinchonine and Cinchona Febrifuge.— We have here grouped together the latest news on the treatment of malaria, more particularly of the benign tertian type. Full details of the chemistry of these alkaloids and their preparations are provided. Much has been written on the treatment of auricular fibrillation with Quinidine Sulphate. The evidence of its efficacy is, on the whole, favourable. Quinine.—“ Quinine in malaria and relapses ” is invariably a difficult subject to review, owing to the extreme divergence of opinions expressed, but on this occasion there is a good paper avail¬ able (p. 714), in which Sir R. Ross lays down the instruction that 10 grains daily, rigorously for three months (84 days), is sufficient in the majority of cases.](https://iiif.wellcomecollection.org/image/b31360440_0001_0021.jp2/full/800%2C/0/default.jpg)


