Volume 1
The extra pharmacopœia of Martindale and Westcott.
- William Martindale
- Date:
- 1920-1921
Licence: Public Domain Mark
Credit: The extra pharmacopœia of Martindale and Westcott. Source: Wellcome Collection.
50/1212 page 8
![Manufacture.—Patented method from Molasses, etc.:— The usual method of manufacture is based on the formation of the Hydro¬ chloride by passing gaseous Hydrochloric Acid into the Molasses—left over after separation of the crystal!i?able bodies. The method in this patent, No. 11,351 of 1912, is stated to be based on accurate knowledge of the con¬ ditions under which Betaine Hydrochloride and the other Chlorides formed are soluble.—P.J ii '12,552. See also C.T). i./io,428. White crystalline substance soluble in water 1 in 2 ; in alcohol about 1 in 20. Uses.—Liberates hydrochloric acid (almost 25% of its weight), and is given with pepsin or well diluted with water in gastric affec¬ tions. Flavoring.—Glyl Rosse, Giyl Menthse Piperitse,SylCaryophyl]i; Syrupus Aurantii. Acetamide. CH3.CO.NH2 = 59*058. Deliquescent crystals M.Pt. 82CC., made by interaction of Ammonia and Acetyl Chloride. As a denaturant (J%) of A1 ohol has been used e g in Phenacetin manu¬ facture Acetamide or Formamide, either molten or in solution, used in extracting drugs.—F. Bayer & Co.’s Patent.—P.J.ii./22,295. ACIDUM BENZOICUM (Off.). Syn. Benzoyl Hydrate. C6H5.COOH=122-083. Dose.—5 to 15 grains (0-3 to 1 Gm.). Manufactured either from Gum Benzoin or from Toluol, the former being the more expensive. Soluble9 if pure, 1 in 400 of water ; 1 in 3 of alcohol 90% ; 1 in 7 of chloroform : and very soluble in fats, oils, alkaline solutions (forming benzoates), and in gfycerin about 1 in 30. Incompatible with Ferric Salts and Mercuric Chloride. Uses.—Benzoic acid is an antiseptic, a stimulating expectorant, antipyretic and diuretic. It is given in cases of chronic cystitis, urinary calculi and incontinence, also for rheumatism,. further in large doses in phthisis, diphtheria, tonsillitis and scarlet fever. It prevents fats becoming rancid, as in Adeps Benzoatus, q.v. Four grains of Benzoic Acid with 1 grain of Canada Balsam, or 1 minim of glycerin, make a good pill. A one in 20 solution in alcohol relieves urticaria, and, as an Anti¬ septic Lotion or Gargle, 1 dissolved in 500 of water is employed, or it may be suspended with glycerin if more than will dissolve. 15 to 20 grains every hour or 2 hours has specific remedial action in acute rheumatism, but is much weaker than Sodium Salicylate. —R. Stockman, B.M.J. i./i3,597. For use as preservative in Foods, etc., see Yol II: Tablets, Compound, v. Index Benzoin.—There are two varieties known as Siam and Sumatra, the former being the best. Sumatra Benzoin is Off if at least 85% soluble in alcohol 90%. For source of Siam benzoin, see Vol. II. Tinctura Benzoin! Cpmposita {Off.). Syn. Friars’ Balsam, Traumatic Balsam. Dose.—i to 1 drachm (2 to 4 Cc.), with yolk of egg. U.S. has approximately same composition as Off.](https://iiif.wellcomecollection.org/image/b31360440_0001_0050.jp2/full/800%2C/0/default.jpg)
