Volume 1
The extra pharmacopœia of Martindale and Westcott.
- William Martindale
- Date:
- 1920-1921
Licence: Public Domain Mark
Credit: The extra pharmacopœia of Martindale and Westcott. Source: Wellcome Collection.
70/1212 page 28
![In the electrolysis of Sodium Chloride, as used in treatment of gonorrhoea, this acid is less decomposed than the salt, and it is able to neutralise the alkalinity which would deposit against the urethral membrane, c/. Gonorrhoea, Therapeutic Index. Acidum Dichloraceticum. CIIC12.C00H=128-946. A colourless caustic for venereal sores. Acidum Trichloraceticum. u.s., p. Heiv., Ph. Ned., p. jao„ CC13.C00H=163-398. Prepared by chlorination of acetic acid, or by the action of fuming nitric acid on chloral hydrate. In deliquescent crystals, M. Pt. 55° C. (lower if moist), and boiling at 195° C., very soluble in water, alcohol and ether. Uses.—A quick escharotic for venereal and other warts. The application of a crystal produces a dry adhering eschar which is quickly thrown off. There is said to be no secondary inflammation. For use as an astringent lotion or gargle, 1 to 5% aqueous solution may be used, and as strong as 1 in 1 or 2 of glycerin wTh a little iodine and potassium iodide has been emp]oyed for temporary application. In ear work it is employed for the closing of perfora¬ tions—a few applications once a week. In cnronic gonorrhoea, solution 1 in 4, is applied on a tampon by means of an endoscope ; less painful than silver nitrate. Also, diluted, for epis taxis. Tobacco stains on the teeth can be removed by its cautious use (25% solution). Tonsils, Diseases of. Where operative treatment is not permitted, the use of Trichloracetic Acid applied on a right angled wool-carrier and passed deeply into the crypts, has been found of value in reducing the size of the tonsil and adding to the comfort of the patient. In Rigg’s disease—incipient stages—this acid applied to the gum after cleaning with Hydrogen Peroxide Solution 10 or 20 Volume, is a good remedy—even curative. The action is probably dual— killing the infective organisms and dissolving the Calcium Carbonate of the tartar. With the disappearance of the tartar the presence of bacteria is excluded. Should be tried before sound teeth are sacrificed. Vincent’s Angina. Trichloracetic Acid stated to be specific.—T. J. Gallaher Pres., Aug. 1920. Chromic Acid applications (saturated solution) also advised. Afterwards gargle with water, later with Hydrogen Peroxide diluted 1 : 10. Further bibliography ibid. Feb., 1921,63. For its use as a delicate test for albumin, v. Vol. II. ACIDUM CINNAMICUM. Cinnamylic Acid.—Syn. Phenylacrylic Acid. C6H5CH : CII.CO.QH —148T09. Dose.—Per os, W to £ grain (0-003 to 0-016 Gm.). Intravenously (in oily emulsion) W to W grain (0-0013 to 0-003 Gm.).](https://iiif.wellcomecollection.org/image/b31360440_0001_0070.jp2/full/800%2C/0/default.jpg)
