Volume 1
The extra pharmacopœia of Martindale and Westcott.
- William Martindale
- Date:
- 1920-1921
Licence: Public Domain Mark
Credit: The extra pharmacopœia of Martindale and Westcott. Source: Wellcome Collection.
94/1212 page 52
![Phthisical sufferers advised to work at bleaching powder factories. Interesting data concerning Chlorine and Nitric Peroxide fumes.-— T. Aitchison, B.M.J. ii./i5,489. Liquor Sodae Chiorinatse (Off.). 2-5% Cl. Dose.—10 to 20 minims. Dissolve Sodium Carbonate 600 in Water 1,000. Tri¬ turate Chlorinated Lime 400, with Water 3,000. Mix, and filter. Should he freshly made. Other Pharmacopoeias use more Sodium Carbonate to obtain a preparation which will keep better. The reaction may be represented as follows :— fCa(C10)2 + Ca012] + 2Xa2C03 = 2NaC10 f 2XaCl + 2CaC03. _ The quantity of Sodium Carbonate in Off. method is not enough to pre¬ cipitate all the dissolved Calcium Hydroxide and if sufficiency is used the preparation is excessively alkaline. it. C. Cowley modifies the formula.— U. D. 1919, 91, 49, abst. Y.B.P. 1919, 230. Uses,—As a wound lotion and for general antiseptic purposes; for infected wounds or ulcers. It is usually employed diluted with 15 to 60 times its volume of water or normal saline. Thus diluted it has been used as a vaginal douche and as an irrigant of the bladder and mouth wash. Locally in skin affections, however, according to the U.S.D. a 10 to 30% dilution is suitable. It is strongly alkaline and may well be treated with Boric Acid, (c/. Dakin’s Solution.) Eau de Labarraque or Liqueur de Labarraque. As made according to the French Codex, this is about \ the strength of Liquor Sodse Chiorinatse (Off.). Much confusion has arisen over this Labarraque’s Solution from several aspects. The United States Pharmacopoeia IX., for example, gives Eau de Labarraque as a synonym for Liquor Sodae Chiorinatse—the strong preparation containing 2'5% available Chlorine. Initially Labarraque made his bleaching solution by passing Chlorine into Sodium Carbonate Solution. In this case free Hypo- chlorous Acid is present: Na2C03 + 4C1 + H20 = 2HC10 + 2NaCl + C02. Eau de Javelle (first made in 1789) was originally a solution of Chlorinated Potash made with Potassium Carbonate on the same lines as Chlorinated Soda Solution, but it is now replaced in great- measure by the Soda Compound. Tor some historical notes on the matter vide H. D. Dakin.—B.M.J. ii./i5,809. Liquor Potassii et Sodii Hypochloritum (Becker). Potassium Hydroxide 5, Sodium Hydroxide 4, Water to 1,000. Dissolve and pass Chlorine q.s. into the solution to saturate. Inoperable cancer has been treated by injections of 1J to 2 Cc. under the skin daily for varying periods over deltoid muscle, or over the great trochanter, avoiding the growth and neighbouring skin. Platinum needle is used. It has been found preferable to make this half strength. Sterules 3 Cc. of this strength are made. , For carbuncles Liquor Sodse Chiorinatse, diluted 1 in 20 or 1 in 30, is a non-irritant and powerful dressing.—S. Phillips, L. i./2i,63.](https://iiif.wellcomecollection.org/image/b31360440_0001_0094.jp2/full/800%2C/0/default.jpg)
