Autoplastic ovarian transplantation and its clinical significance / by J.H. Nattrass.

  • Nattrass, John Hodgson.
Date:
1910
Catalogue details

Licence: In copyright

Credit: Autoplastic ovarian transplantation and its clinical significance / by J.H. Nattrass. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    Autoplastic Ovarian Transplantation and Its Clinical Significance. From the Physiological Laboratory, Univ(M‘sity of Melbourne. The possibility of removing the ovaries from their normal position in the female body and grafting them on to various other ])arts of the same or different animals, is a subject which has been receiving a lot of attention during the last few years from researchers in Eurojre and .Vnierica. Being exceedingly interested in the subject and desirous of seeing what would be the result of such experiments in our own laboratory,* I determined to carry out a series of experi- ments in order to confirm or otherwise, and if possible to elab- orate, the results previously obtained. In the first place, I had to determine the most suitable animal on which to conduct these experiments. I found on examining the literature on this subject that rabbits had been most ex- tensively used,^ chiefly by Knauer, Limon, Grigorieff, Ru- benstein and Foa, whilst Flalban, Herlitzka, Scnultz, and Rib- bert experimented with guinea-pigs, Knauer, Marshall and Jolly with hitches: Halban used monkeys, Marshall and Jolly- used rats, and Guthrie''* transplanted the ovaries of chickens. I found records also of five surgeons, viz., Morris,'* Glass, Dudley, Cramer.and Tuffier, who had en- deavoured to trans])lant ovaries in the 'human being. I de- cided in my experiments to work first of all with the bitch, chiefly because of the ease with which it could be obtained and kept, and because of its great resistance to anaesthetic and op- erative measures ; but I soon found that because of the peculiar anatomical arrangement of its tubes and ovaries, it was quite unsuited for my purpose, the ovary being surrounded by a sac, formed by the dilated abdominal end of the tube, which made it difficult to know when it was completely excised^. * I express my indebtedness to Professor Osborne for placing his laboratory at my disposal, and for much valuable advice; also to the Rev. W. Fielder, in whose department the microscopic sections were prepared, and Mr. W. J. Owens for the micro-photography.