Researches on phthisis, anatomical, pathological and therapeutical.
- Pierre Charles Alexandre Louis
- Date:
- 1844
Licence: Public Domain Mark
Credit: Researches on phthisis, anatomical, pathological and therapeutical. Source: Wellcome Collection.
Provider: This material has been provided by the Harvey Cushing/John Hay Whitney Medical Library at Yale University, through the Medical Heritage Library. The original may be consulted at the Harvey Cushing/John Hay Whitney Medical Library at Yale University.
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![alteration of structure. In three out of sixty cases ulcerations displayed themselves, varying in diameter from one line to one line and a half [2 to 3 millimeters], and in number from three to ten, and of pale colour in two cases. (Case ix.) In the third case there were two from three to four and a half lines [6 to 9 millimeters] in diameter; here the fundus was blackish, and formed, as in the preceding cases, of the submu- cous cellular tissue, somewhat thickened. The mucous membrane presented no remarkable appearance in their neighbourhood. In the cases where the ulcerations were small the liver con- tained cysts, no less small, filled with a greenish pulpy matter; but there was no connexion between the gray or pink colour of the mucous membrane of the duodenum, the enlargement of the mucous follicles, and the passage of the liver into the fatty state. I once found a fibrous tumour, of the same kind as those so common in the uterus, in the muscular coat of this part of the intestine; it was about the size of a hazel-nut. Since the publication of the former edition of this volume 1 have again studied with attention the state of the mucous mem- brane of the duodenum in phthisical subjects ; in sixty of them I found nine cases of ulceration,—a higher proportion than that before noticed, and probably arising from my examination having been more complete. The mucous membrane was more or less red, and somewhat softened in four cases ; in one instance there were a few submucous tubercles discernible. The state of the duodenum did not present precisely the same characters after other chronic diseases as in the victims of phthi- sis ; sixty-five subjects furnished only one case of ulceration. SECTION IV.- Before describing the various lesions of the small intestine, it may be well to direct the reader's attention to the natural 1 A close analogy may be discovered between several remarks made in this section and those of Billard in his work upon the ' Gastro-intestinal mucous membrane.' Without meaning to attaeli too much importance to my own observations, I may yet](https://iiif.wellcomecollection.org/image/b21015235_0107.jp2/full/800%2C/0/default.jpg)
