Researches on phthisis, anatomical, pathological and therapeutical.
- Pierre Charles Alexandre Louis
- Date:
- 1844
Licence: Public Domain Mark
Credit: Researches on phthisis, anatomical, pathological and therapeutical. Source: Wellcome Collection.
Provider: This material has been provided by the Harvey Cushing/John Hay Whitney Medical Library at Yale University, through the Medical Heritage Library. The original may be consulted at the Harvey Cushing/John Hay Whitney Medical Library at Yale University.
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![When of small dimensions, these ulcerations almost invariably presented themselves opposite the mesentery, in the situations once occupied by the patches of Peyer, which were now imper- ceptible, having indeed been completely destroyed; when of the largest dimensions observed, they extended round the entire circumference of the bowel. They varied in superficial extent from two lines to eighteen or twenty-two inches [4 millimeters to 45 or 55 centimeters]. In certain cases several ulcerations of these latter dimensions existed in the same subject, (Case iv;) whereas, in others a few only, or even but one, of the smaller kind were discernible. (Case xvi.) Their shape generally indicated their mode of origin, and varied as their dimensions. When small, they were round, like those succeeding to the softening of granulations; when of medium size, they presented an elliptical form, like the glan- dular patches in which they originated; the latter was the most general shape; next in order came the annular. (Cases xxix, xxxiv, liv.) The linear was the most uncommon form; still I have observed it in seven cases, almost invariably in the upper half of the intestine: the ulceration, under these circumstances, measured from an inch and two lines to two inches [3 to 5 cen- timeters] in length, by one and a half to two lines [3 to 4 millimeters] in width at its central part; being at the same time narrower at both ends. The colour of the ulcerations was not less varied than their other attributes. Generally whitish when they were of small size, it was often gray and red, when they were of medium or less dimensions. Sometimes also, but solely in the case of the long and narrow ulceration, their colour was blackish or red- dish brown. The structure of the ulceration varied with their extent and their length of duration. When small, and no doubt recently formed, the submucous cellular tissue was laid bare, somewhat thickened and smooth, and the muscular tunic not obviously altered in characters. When of larger size they exhibited a more varied aspect. The surface of some of them was uneven and formed of the submucous tissue, more or less thickened, and some shreds of mucous membrane. In others, no traces re- mained of the latter coat; the mucous membrane was alternately](https://iiif.wellcomecollection.org/image/b21015235_0115.jp2/full/800%2C/0/default.jpg)
