"606" in theory and practice / by Paul Ehrlich and J.E.R. McDonagh.

  • Paul Ehrlich
Date:
1911
Catalogue details

Licence: In copyright

Credit: "606" in theory and practice / by Paul Ehrlich and J.E.R. McDonagh. Source: Wellcome Collection.

    53/166 page 35
    as. this procedure has in some eases resulted in toxic symptoms supervening, such as anuria, inflammation of the bladder, and atony of the large intestine. Clincal Course after an Intramuscular Injection.—How- ever the solution be prepared, and however carefully it may be given, one can never say beforehand how much pain the patient is going to suffer. Some patients have little or none, whilst others, on the other hand, have excruciating pain which may last as long as a week. Needless to say, the very greatest precaution should be taken in sterilizing everything before its use; since if an abscess forms, the pain will necessarily be severe. Even when the strictest antiseptic precautions are taken, swelling, softening, and necrosis of the part injected may take place. The swelling is of the nature of a toxic oedema. It comes on about the third day, diminishes in size at the end of a week or ten days, after which time its diminution is very gradual and a small amount of in- filtration may be perceptible for months after. Asa rule the swelling is not painful ; it gives the appearance of fluc- tuation, but under no circumstances should it be opened, unless an obvious abscess forms, when the swelling becomes acutely painful. The skin over it is usually of normal hue; when the swelling first appears, the skin may be red, but if the skin becomes red for the first time
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