The fever of over-exertion / by J.F. Knott.

  • Knott, John, 1853-1921.
Date:
1888
Catalogue details

Licence: Public Domain Mark

Credit: The fever of over-exertion / by J.F. Knott. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    Methene cyan-alcohol. ^OH .NH2 GET + NH3 = CH.C: + HjO. ^CN ^CN Glycocine. .NH2 .NH, CB,:^ + 2H2O = CH,.^ + NH3. ^CN '^CO.OH FATE OF GLTCOOINE IN THE HUMAN ECONOMY. (A.) THE WAY IN WHICH IT SHOULD GO. Through the kidney as urea. Products of oxidation of— Glycocine. Carbamic acid. Oxamic acid. Oxalic acid. NH2 NH2 CO.NH2 CO.OH ^CO.OH CO.OH CO.OH CO.OH (B.) THE WAY IN WHICH IT SHOULD NOT GO. Glycocine. Urea. Hydantoic acid. ^Hj NH^ NHj CH^::; + co^ = coc^ + NH3 ^CO.OH ^NHa ^NH—CHa—CO.OH \, Hydantoic acid. Hydantoin. /NH^ ^NH—CO CO2:; + H,0 = CO^ ^NH—CH,~CO.OH ^NH—CH, Biuret. Urea. NH, /NH, CO^ 2C0:; = ^NH + NH, } (2) ^NH2 COCf ' ^ ^NH Biuret. Hydantoin. NH, NH—CO COC^ Ammonium Urate. CO + ^NH = C5H3N,03.NH,. + H,0. [? GOUT.] ^NH—CH, COCf ^ ^NH, By the chemical changes here indicated we have glycocine, formed from the methene cyan-alcohol gi-oups, detached by the disintegi-ation of the albuminoid molecules. This body, by conjugating with urea, forms hydantoic acid, ammonia being at the same time separated. Biuret is formed by condensation of urea molecules, as here represented—a process which is also