A handbook of local therapeutics / edited by Harrison Allen.

Date:
1893
Catalogue details

Licence: Public Domain Mark

Credit: A handbook of local therapeutics / edited by Harrison Allen. Source: Wellcome Collection.

    274/554 (page 262)
    around the wound, wash out with the corrosive solution, and then cau-] terize with a hot iron. In the genito-urinary tract corrosive sublimate has an extensive field of -use, depending almost entirely upon its antiseptic properties. In the! treatment of Gonorrhcea J. W. White {^Public Clinic) is in the habit of using an injection of solution of corrosive sublimate in strength from one-quarter to one-half grain to an ounce in combination with boric acid, and sulphocarbolate of zinc. The following prescription is also recommended: R. Hydrarg. bichlor., gr. ii-iv; zinci sulph. carbolat., gr. ii-x j acidi Borici, 3]; hydrogen, peroxidum, §j; aquse, q. j.,ad. gviij. Bichloride of mercury is used in varying strengths up to as high as i-iooo with the object of aborting the disease. We have seen solutions of 1-2000 cause severe pain and increase the grade of inflammation in the first stage of Acute Gonorrhcea. E. L. Keys Genito-Urinary Disease with Syphilis, p. 66) states that he has never been able to entirely arrest a true gonorrhoea at once with corrosive sublimate, or to kill the micro- coccus. The irrigating of the urethra in a mild solution (1-20,000, 1-40,000), as advised by Halstead, to be used wiih a fountain syringe, is often followed by good results. In our experience the treatment with bichloride solutions is inferior to that obtained from solutions of salts of zinc and lead, with opium. In Specific Vaginitis or Gonorrhoea, in the female, the solution o^'lfi corrosive sublimate has been found a reliable means of treatment. It can be borne much stronger than in the male, as a rule, without causing pain. It may be used in strength from 1-4000 to 1-10,000, beginning with the weaker solution. Corrosive sublimate is in constant use as an antiseptic in uterine and vaginal surgery, as, for example, in operations for lacerated cervix, ruptured perineum, etc., as well as for flushing the uterus after childbirth. In obstetric practice creolin {q. v.) is being sub- stituted largely for this agent with equally good results and little danger of producing toxic symptoms. Diseases of the Skin.—Bichloride of mercury has been long and extensively used in the local treatment of diseases of the skin. In hypertrophic affections of the epidermis, as Lentigo, a solution of two to four grains of bichloride of mercury to the ounce of alcohol painted on the skin a number of times successively causes an exfoliation, which, in time, relieves the skin of the brown discoloration. A solution of ten to twenty grains to the ounce of collodion is effectual in the removal of superficial N^evi and Xanthoma. In Telangiectasis a twenty- grain solution painted on daily for several successive days causes the formation of a white crust, which after a time separates and the growth is found to have been destroyed. Such solutions must be used with great caution. i