Volume 2

Animal chemistry with reference to the physiology and pathology of man / by J. Franz Simon ; translated and edited by George E. Day.

  • Johann Franz Simon
Date:
1845
Catalogue details

Licence: Public Domain Mark

Credit: Animal chemistry with reference to the physiology and pathology of man / by J. Franz Simon ; translated and edited by George E. Day. Source: Wellcome Collection.

Provider: This material has been provided by King’s College London. The original may be consulted at King’s College London.

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    their colour brown or yellow. Internally they present a de- cidedly crystalline character^ they are white or yelloAV^ and often contain a minute cavity in the centre, of a darker colour than the rest of the concretion, and presenting an incrusted appearance. Wittingi found in a human gall-stone cholesteriu 50; resin and colouring matter insoluble in ether 35; carbonate of lime 8, water 5. The folloAving analyses of human gall-stones were made by Glaube and Brande: Glaube. ^ 1. Brande. 2. 3.^ Cholesterin 56 81-25 69-76 81-77 Biliary resin 8 312 5-66 3-83 Bile-pigment 15 9-38 11-38 7-57 Albumen with mucus and salts extract- -i able by water . . / — — 3-83 Coagulated albumen 9 — — — Biliary mucus 12 6-25 13-20 — In addition to the ordinarv constituents Von Bibra^ found 1-52 of aluminawith iron, and 1-42 of carbonate of lime in a biliary calculus; and Witting, as I have already observed, detected a considerable amount of the latter constituent in a concretion of this nature. An extraordinary quantity of this earth was found by Bally and Henry in a gall-stone; it consisted of carbonate of lime with traces of carbonate of magnesia 72'70, phosphate of lime 13’51, mucus, with a little peroxide of iron and bile- pigment, 10‘81. [Schmidt and Wackenroder have recently published analyses of human biliary calculi, consisting principally of colouring matter. Archiv der Pharmacie, vol. 41, p. 291.] Berzelius mentions another kind of gall-stone, consisting principally of carbon; at le’ast it is insoluble in water, alcohol and ether, acid and alkaline fluids; when heated to redness in a retort, undergoes no alteration, but when burned in oxygen, after giving ofl' slight traces of smoke, takes Are, and burns Avithout flame or residue, with the formation of carbonic-acid gas. I have recently examined a biliary calculus found in the gall-bladder of an officer aaAio died from cerebral and spinal irritation, and -incipient softening of the ner\'Ous tissue: in ' Ardiiv der Pharm. vol. 25, p. 292. “ Journ. fiir piakt. Cheinie, vol. 12, p. 311.