Fibromata and cysto-fibromata of the ovary / by Harry C. Coe.
- Coe, Henry C., 1856-1940.
- Date:
- 1882
Licence: Public Domain Mark
Credit: Fibromata and cysto-fibromata of the ovary / by Harry C. Coe. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![stnieture' (and hence like the normal stroma), though with this difference—the fibres were loosely interlaced, in places widely separated, so as to leave interstitial spaces, which were occa- sionally packed with lymphoid cells. This tumor was also much more vascular than the other, showing the presence, not only of dilated vessels, but of many blood-extravasations. ISTo degenerative changes, strictly speaking, were to be found. The general aspect of all the sections suggested the existence of a wide-spread edema, which had softened and separated the fibres, rendering the resemblance of the tissue to that of a myxoma very complete. With a higher power (h obj.), the appearances in the neighborhood of the cyst were as follows: As the observer apj)roached its wall, the loose tissue became somewhat denser in structure, the spindle-cells no more numei’- ous, but in closer proximity to one another, until at the edge of the cavity they were arranged in parallel rows, and placed end for end, especially the most internal layer. It was easy to imagine how a row of these swollen cells, placed in regular order, could be mistaken on hasty examination for the remains of an endothelial lining, when their focus is a little different from that of the remainder of the field. G-roups of round connective-tissue cells were not wanting; those of the branched variety were not so well defined. But of especial interest was the presence of collections of blood-corpuscles adjacent to the cyst, some of which were evidently derived from neighboring vessels, while the source of others coiild not be found. All through the tissue, little groups of three or four blood-cells might be seen, and the more carefully the sections were scrutinized, the more it appeared that this condition was a gen- eral one throughout the specimen, though most noticeable at the ' The arrangement of fibres and spindle-cells reminded the writer of a very interesting “recurrent fibroid” of the breast which he had an op- portunity of studying. Since writing this paragraph, the following passage from Klebs was observed: “Between the coarse muscular bundles, as well as between these and the connective-tissue sheaths of the vessels, may be observed everywhere narrow, slit-like gaps, which contain white blood corpuscles and are surrounded by a fine boundary line, within which here and there he nuclei. A cavernous structure thus originates, which is not found in the normal (uterine) tissue, and it is very probable that these cavities are to be regarded as lymph-spaces in which the blood-vessels and muscular bundles are suspended, as it were, by fine bands of connective tissue ’ (.Handbuch der Path. Anat., 4th edition.]](https://iiif.wellcomecollection.org/image/b22336400_0025.jp2/full/800%2C/0/default.jpg)
