An inquiry into the causes and effects of the variolae vaccinae : a disease discovered in some of the western counties of England, particularly Gloucestershire, and known by the name of the cow pox / by Edward Jenner ... ; from the second London edition.
- Jenner, Edward, 1749-1823.
- Date:
- 1802
Licence: Public Domain Mark
Credit: An inquiry into the causes and effects of the variolae vaccinae : a disease discovered in some of the western counties of England, particularly Gloucestershire, and known by the name of the cow pox / by Edward Jenner ... ; from the second London edition. Source: Wellcome Collection.
Provider: This material has been provided by the National Library of Medicine (U.S.), through the Medical Heritage Library. The original may be consulted at the National Library of Medicine (U.S.)
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![t io ] years old, for the purpofe of inoculation for the Cow Pox. The matter was taken from a fore on the hand of a dairymaid*, who was infected by her matter's cows, and it was inferted, on the 14th of May, 1796, into the arm of the boy by means of two fuperficial incifions, barely penetrating the cutis, each about half an inch long. On the feventh day he complained of uneafineft in the axilla, and on the ninth he became a little chilly, loft his appetite, and had a flight head-acrw During the whole of this day he was perceptibly indifpofed, and fpent the night with fome degree of reftleffhefs, but on the day following he was per* feclly well. The appearance of the incifions in their progrefs to a ftate of maturation were much the fame as when produced in a fimilar manner by variolous mattert. The only difference which I perceived was, in the ftate of the limpid fluid ariflng Irom the aftion of the virus, which aiTumed rather a darker hue, and in that of the efflorefcence fpreading round the incifions, which had more of an eryfipelatous look than we commonly perceive when variolous matter has been made ufe of in the fame manner ; * From the fore on the hand 0/ Sarah Nelmes.—See the preceding cafe and the plate. + This appearance nuat in great meafure new to me, and I e~oer floall recolleil the plcafing fenfations it ex- cited ; as, from its Jimilarity to the pujlnle produced by •variolous inoculation, it incontejiibly pointed out the clofe connexion between the two dfcafes, and altnoft anticipated the refult of my future experiments.](https://iiif.wellcomecollection.org/image/b21133268_0028.jp2/full/800%2C/0/default.jpg)