The intensive treatment of syphilis & locomotor ataxia by Aachen methods.
- Hayes, Reginald Hewlett.
- Date:
- 1914
Licence: In copyright
Credit: The intensive treatment of syphilis & locomotor ataxia by Aachen methods. Source: Wellcome Collection.
Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.
12/80 (page 4)
![The steady advance of medical science will, per- haps, eventually lead to the substitution for spiro- chseticidal drugs of a vaccine or serum. Already, indeed, something has been done in this direction by injecting salvarsanized serum into the cerebro- spinal fluid, by means of lumbar or cranial puncture, in those suffering from the later effects of syphilis of the central nervous system, such as tabes and general paralysis. This form of medication by in- jection into the cerebro-spinal fluid was suggested in 1911 by Marinesco, of Bucharest [2], for the treatment of general paralysis, and its application to tabes dorsalis elaborated by Swift and Ellis, of the Rockefeller Institute, in New York. This or some modification of the method has now been tried fairly extensively, with results which are said to be most encouraging in some instances. The good effect so obtained is attributed to the presence of antispirochaete antibody and minute traces of sal- varsan in the serum, which can be prepared either from human beings or certain animals. A later plan—namely, the injection directly into the cerebro- spinal fluid of a solution of neo-salvarsan—has been given a trial by Ravaut [3], of Paris, who expresses himself as by no means satisfied with the outcome. Apropos of lumbar puncture, however, it may not be out of place here to remark that, apart from risk of myelitis, its indiscriminate use is to be most strongly](https://iiif.wellcomecollection.org/image/b21518506_0012.jp2/full/800%2C/0/default.jpg)
