Investigations concerning bovine tuberculosis : with special reference to diagnosis and prevention / conducted under the direction of D.E. Salmon.
- Date:
- 1894
Licence: Public Domain Mark
Credit: Investigations concerning bovine tuberculosis : with special reference to diagnosis and prevention / conducted under the direction of D.E. Salmon. Source: Wellcome Collection.
35/196 page 31
![Number in which portal and not mesenteric glands affected 4 Number in which parenchyma of liver involved 2 Number in which serous membranes affected 2 Number in which udder glands affected 1 SUMMARY OF TUBERCULIN REACTION AND AUTOPSY NOTES. [The clinical notes and the tuberculin reactions were supplied by Drs. Ivilborne and Schroeder. For the autopsy notes Dr. Smith is responsible.] No. 301.—Cow, three-fourths Holstein, 4 years old. Weight, 850 pounds. Calved summer of 1892; still giving milk. Pregnant since August 21,1892. Condition good. February 2,1893: 9 a. m., first injection, 0.25 cc. tuberculin S.; 6 toT ^. m., periods of trembling observed. Feces softened and passed more frequently than usual. Cefore injection, minimum temperature, 100.1° (10 a.m.); maximum, 102° (3 p.m.). After injection, minimum temperature, 101.2° (1 p. m.); maximum reached in twelve hours, 106.8° (9 p. m.). (For complete record see p. 60.) March 21, 1893: Midnight, second injection, 0.4 cc. tuberculin K. Before injec- tion, maximum temperature, 102.7° (4 p. m.); ^ after injection, reached in sixteen hours, 106.5° (4 p.m.). (For complete record see p. 69.) March 24, 1893: Killed for examination. Autopsy.—Thorax: All the bronchial and posterior mediastinal glands infected. The disease appears as foci of grayish infiltration in which are delicate networks of yellowish lines (necrosis). The foci are up to one-half inch in diameter and all appear to be in about the same stage. Lungs: Trachea and bronchi free from any visible tuberculous changes. Abdomen: One mesenteric gland contains a focus about three-eighths inch in diameter completely transformed into gritty particles. One gland at the portal fissure contains a tuberculous focus about one-half inch in diameter in which the disease process is perhaps somewhat farther advanced than in the bronchial glands. No. 30,?.—Holstein COW; 5 years old. Weight, 850 pounds. Calved July, 1892; still giving milk. Pregnant since September 30,1892. Condition good. February 2, 1893: 9 a.m. first injection, 0.25 cc. tuberculin S.; 5 to 10 p. m., jjulse fuller and stronger than before injection. Respiration somewhat accelerated. Feces softened. Before injection, minimum temperature, 100° (9 a. m.); maximum, 102.2° (4 p. m.). After injection, minimum temperature, 101° (1 p. m.); maximum, reached in ten hours, 107.4° (7 p. m.). (Fop complete record see p. 60.) March 21, 1893: Midnight, second injection, 0.4 cc. tuberculin K. March 22: 10 a. m., periods of slight trembling observed. Before injection, maxi- mum temperature, 102.2° (6 p. m.); after injection, reached in twelve hours, 106.8° (12 a. m.). (For complete record see p. 69.) * March 24,1893: Killed for examination. J ?tfoj;s^.—Thorax: The caudal two-fifths of right caudal lobe of lungs completely tuberculous. The disease appears most advanced along the cephalic border of the involved mass. Here the lung tissue is transformed into soft caseous masses con- taining some gritty particles, which are over one-half inch in diameter and inclosed in connective tissue capsules. Toward the caudal extremit}^ of the lobe the foci are yellowish, necrotic, but not yet broken down, excepting in a few cases. The bronchus contains a few soft grayish and some caseous tubercles breaking through the mucosa. There are several cheesy masses lying free on the mucosa. At bifur- cation there are two irregular spots on the mucosa of trachea one-half inch in diameter, made up of young and caseous tubercles. *In giving the hour of minimum and maximum temperature when the same occurs more than once the hour of first occurrence is given.](https://iiif.wellcomecollection.org/image/b21783111_0035.jp2/full/800%2C/0/default.jpg)
