Investigations concerning bovine tuberculosis : with special reference to diagnosis and prevention / conducted under the direction of D.E. Salmon.
- Date:
- 1894
Licence: Public Domain Mark
Credit: Investigations concerning bovine tuberculosis : with special reference to diagnosis and prevention / conducted under the direction of D.E. Salmon. Source: Wellcome Collection.
40/196 page 36
![3B near the focus its mucosa is sprinkled with grayish tubercles. The affected lung tissue contains mucli connective tissue inclosing calcareous foci. There are very few apparently fresh tubercles. The posterior mediastinal glands are all affected. The most caudal of the series is considerably enlarged, and contains five dry, largely calcareous foci up to one-half inch in diameter. There is, in addition, in one end of the gland a considerable development of fresh, grayish tubercles; the same is true of the opposite end of the gland. The second gland of the series contains a small, calcareous focus about oue- eighth inch in diameter. The third gland, about 1 inch in diameter, contains three or more similar foci. Its exterior is more or less nodalated and retracted^ The fourth gland contains two similar foci and some recent infiltration. The fifth is in the same condition as the fourth. The sixth gland contains two similar foci. These glands are moderately enlarged. The bronchial gland, situated on the root of the left bronchus is about 1} inches in diameter, of slightly irregular outline, and con - tains in its center a partly calcareous focus one-half inch in diameter and several small foci of more recent origin. The other bronchial glands are also involved. Abdomen: On the peritoneal aspect of the diaphragm and attached to the reticu- lum is a tumor about 1^]- inches in diameter, containing a small quantity of creamy pus within a dense connective tissue capsule, and surrounded by a considerable quan- tity of gelatinous-looking connective tissue (traumatism due to foreign body from reticulum). No. 313.—Cow, fifteen-sixteenths Holstein, 6 years old. Is giving milk. Pregnant since November 25, 1892. March 16, 1893: 9 a. m., first injection, 0.2.5 cc. tuberculin S. 9 p. m., periods of slight trembling observed. 10:20 p. m., the trembling is very marked, but ceases by 11 p. m. The long hay not eaten this evening. March 17, 2 a. m.: Several periods of slight trembling. Before injection, minimum temperature, 99.4° (10 a.m.); maximum, 102.3° (4 p. m.) After injection, minimnm temperature, 100.6° (11a. m.); maximum, reached in fourteen hours, 106.6° (11 p. ra.). (For complete record see p. 63.) March 27, 1893, midnight: Second injection, 0.4 cc. tuberculin K. Before injec- tion, maximum temperature, 102.4° (4 p. m.); after injection, reached in thirteen hours, 104.4° (1 p. m.). (For complete record see p. 69.) April 7, 1893 : Killed for examination. Autopsij.—The only tuberculous lesions found in this animal are two soft masses, about one-half inch in diameter, in the bronchial gland at the root of the left bronchus. With a small quantity of this caseous material 2 guinea-pigs were inoculated sub- cutaneous] y. One killed two and one-half months after inoculation showed an ulcer at the place of inoculation and the neighboring lymphatics caseous. The spleen and liver con- tained masses of tubercles, the retrogastric and the bronchial glands were enlarged and necrotic. The second, killed in a dying condition three months after inoculation, showed very extensive tuberculous changes in liver, spleen, and lungs. In the cow there is considerable enlargement of all thoracic lymph glands, prob- ably due to traumatic pneumonia, resulting from the passage of a foreign body from the reticulum through the diaphragm. On the serous aspect of the reticulum there is a patch of gelatinous tissue, about 6 by 8 inches square and from one-half to 1 inch thick, attaciiing it to diaphragm. The nearest lymph glands of the paunch are enlarged and contain creamy pus. In the thorax the right ventral lobe is enlarged, very firm, and adherent to ribs and diaphragm. A tubular connective tissue passage extends from diaphragm into the affected lobe. The phrenic end is now closed. When this passage was cut a milky pus of penetrating but not offensive odor flowed out from a cavity in the affected](https://iiif.wellcomecollection.org/image/b21783111_0040.jp2/full/800%2C/0/default.jpg)
