Provisional report on healing of arteries after ligature / by J. Collins Warren.

  • John Collins Warren
Date:
1884
Catalogue details

Licence: Public Domain Mark

Credit: Provisional report on healing of arteries after ligature / by J. Collins Warren. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    THE HEALING OF ARTERIES AFTER LIGATURE. [The accompanying statement embodies the results of several years of experimental investigations on animals and the examina- tion of specimens taken from the human subject. Owing to the inability of the writer to prepare an elaborate paper at the present time, he has been obliged to content himself with publishing this brief summary of remarks made at the meetings of the Boston So- cietj’- for Medical Sciences during several successive seasons, and reported in their records of March 20, 1883.] Investigators who have interested themselves in the process of repair in arteries have considered the ques- tion usually from some special stand-point such as “ the organization of the thrombus,” “ the part played by the white corpuscles,” “ the endothelium,” etc. The object of this paper is to study the various pathological changes which occur in and around the vessel from the time the ligature has been applied until the process of cicatrization has fully completed itself. These changes may be compared not inaptly to those which occur in long bones after fracture. In both we find an external and an internal callus, the former hav- ing only a provisional existence in the case of arteries, and subsequently giving place to a ligamentous union of the divided fragments, the latter undergoing such changes in the later stages of the process that the canal or lumen of the vessel is imperfectly reestablished by the so-called “canalization ” of the thrombus. In the mean time the walls of the vessel, like the cortical bone, have undergone certain changes which enable them to participate in the final process of repair.