Two monographs on malaria and the parasites of malarial fevers / I. Marchiafava and Bignami, II. Mannaberg.

  • New Sydenham Society
Date:
1894
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Licence: Public Domain Mark

Credit: Two monographs on malaria and the parasites of malarial fevers / I. Marchiafava and Bignami, II. Mannaberg. Source: Wellcome Collection.

Provider: This material has been provided by The University of Leeds Library. The original may be consulted at The University of Leeds Library.

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    tow ever, it does not imply, as will be seen from what has just been said, that all forms with quiescent pigment must be dead. Mai'chiafava and Celli [19] have described the occurrence of an imdulating edge in various spherical bodies (as appears from their description of those of the crescent series) ; Councilman once saw a crescent with a wave-like movement of its edge. I have several times observed the undulating movement of the edge of the spherical bodies of the crescent series, but I got the impression that this phenomenon was caused by the flagella which had not been able to break through the relatively strong membrane of the spherical bodies. If the eruption of the flagella is often observed, it is not infrequently noticed that in the pre- paration for this process the undulating edge is noticed for several seconds. A similar, if not exactly the same, opinion appears to be held on this subject by Danielewsky [75]. He writes : It appears to me that this undulating form can produce itself from the one described above by the gradual drawing in of the flagella. After this I do not think it justifiable to consider the undulating edge as a movement in a special category, but I perceive in it only a modification of the flagella movement, which is produced by the resistance of the membrane ; it is a Jlagella movement within the membrane. (e) Concerning the relation of the parasite to the red blood-cor- puscles.—From the time of his discovery onwards, Laveran was of the opinion that the parasites existed, partly free in the liquor sanguinis, partly adherent to the red blood-corpuscles or pressed into ( accole) their upper surface, and he holds to this opinion to the present day. Richard [11], on the other hand, was of the opinion at the commencement of his investigations that the parasite was developed within the red blood-corpuscles, and that after becoming large in them they left them by rupture of the membrane. Later [81] he gave up this idea and returned to Laveran's opinion of the extra-corpuscular existence of the parasite. Among the Italians it was Marchiafava and Celli who most strenuously defended Richard's first view that the parasites existed within the red blood-corpuscles and that they are there- fore endo-corpuscular parasites. As chief argument they brought forward the fact that the amoeboid parasites never overlap the border of blood-corpuscles, which must sometimes occur if they only lie upon them and are not held fast to their substance. Further, they noticed in this connection the consideration that if Laveran's view were correct a parasite must occasionally come