A report of microscopical and physiological researches into the nature of the agent or agents producing cholera : second series / by T.R. Lewis and D.D. Cunningham.
- Timothy Richards Lewis
- Date:
- 1874
Licence: Public Domain Mark
Credit: A report of microscopical and physiological researches into the nature of the agent or agents producing cholera : second series / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.
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![[ » ] experiments on as many dogs. In ten of the experiments the material injected into the blood was simply strained, and in thirteen the fluid was first subjected to heat, then allowed to cool and strained before being employed. A tabulated statement of the first-mentioned class of experiments is annexed:— TABLE XV. (a).—The Choleraic material introduced being Fresh and Not subjected to Heat. Experiment No. XXII XXIII XXIV XXV XXVI XXVII \ I.IN BELECTBD. Femoral Saphena. o a ill I Four Four Four Two Four Four 6= < Kkmauks. The material injected consisted of almost colorless watery fluid. Death resulted in 5 hours without marked intestinal symp- toms. Although the post-moriem exami- nation was conducted within 2 hours after death, the stomach and intestines were en- ormously distended with gas: the intestinal glands could be seen very distinctly through the distended walls of the gut. The mucous surface was disorganised, and presented all the characters of acute septic enteritis ; lungs collapsed ; the splanchnic nerves and semilunar ganglia apparently unaffected. Temperature at the time of the operation 102° in the vagina. Next day 104 in rectum, but 102 in vagina: appeared un- affected till the fourth day, when it was killed under chloroform. All the viscera were healthy. The bladder full of urine (sp. gr. 1012), and the intestinal contents quite normal. The fluid injected was nearly colorless (sp. gr. 1004), and contained a few red blood- corpuscles. The dog died in about 18 hours. The intestines presented the ap- pearance usual in gastro-enteritis. The blood was crowded with crystals, but not a trace of bacteria could be detected. On the second day the temperature was 104°5, on the 3rd 103°, on the 4th 104,° when the animal died. There were no spe- cial post-moriem appearances, except in the liver, where numerous minute embolic patches were visible and considerable softening. Death evidently due to em- bolism. Death in 7 hours. Death in 6 hours. The same material used as in Exp. XXVI.](https://iiif.wellcomecollection.org/image/b20395607_0052.jp2/full/800%2C/0/default.jpg)
