Collected papers on pharmacology and therapeutics.

  • Phillips, Charles D. F. (Charles Douglas Fergusson), 1830-1904.
Date:
1908
Catalogue details

Licence: In copyright

Credit: Collected papers on pharmacology and therapeutics. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

    90/288 (page 78)
    powder, freely soluble in cold water, and soluble with difficulty in hot water. The ordinary dose for administration by mouth is from three to ten grains, or from two to four grains hypodermically. Amongst other salts may be mentioned the gly- cerophosphate of iron, which is met with either as a whitish powder or in scales, the glycerophos- phate of sodium, which is a translucent, straw- coloured pasty mass, and the glycerophosphates of potassium, lithium, magnesium, manganese and quinine. A useful preparation of the glycerophos- phates is made by dissolving two parts each of glycerophosphate of sodium and lime, and one part of glycerophosphate of iron in two hundred and fifty parts of aromatic syrup. The dose is from two to four drachms. Discovered in the yolk of egg in 1846, glycero- phosphates were but little known before 1893, when Robin drew attention to the large amount of partly oxidised phosphorus in the form of glycerophosphoric acid eliminated in the urine of some neurasthenic patients ; having obtained and administered compounds of this acid, he concluded that they increased the general metabolism of both organic and inorganic matter, principally the latter, as shown by augmented excretion of urea, chlor- ides and sulphates, though not of uric acid nor of phosphates ; at the same time they favoured the current assimilation of the albuminoid matters, and moderated denutrition of the nervous system