Lyovac : normal human plasma, irradiated / Sharp & Dohme.

  • Merck & Co.
Date:
[1950?]
Catalogue details

Licence: Public Domain Mark

Credit: Lyovac : normal human plasma, irradiated / Sharp & Dohme. Source: Wellcome Collection.

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    now irradiated - af | Seer TO RERUCE RISK OF HOMOLOGOUS SERUM HEPATITIS! ite, Se —$_$____—_—— The rationale for the use of plasma as a substitute for whole blood has been established by many workers, particularly for such indications as shock with or without hemorrhage,'” burns,’* restora- tion and maintenance of body proteins,’ and for theemergency treatment of severe hemorrhage.'”” Clinical Indications SHOCK: In shock, the marked fall in blood pres- sure with resultant failure in circulation results from the decrease in blood volume due to the loss of fluids through the capillary walls into extra- vascular tissue spaces. Since plasma proteins are colloidal and diffuse slowly, they are not lost from circulation as readily as crystalloids. Plasma may, therefore, be used more effectively to regulate and maintain blood volume.? BURNS: In severe or extensive burns there is a marked loss of fluid containing large amounts of plasma proteins. This loss is further enhanced by the increased capillary permeability throughout the entire body due to the liberation of toxic substances from the burned area. As a result,
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