Serums, vaccines and toxines in treatment and diagnosis / by Wm. Cecil Bosanquet ... and John W.H. Eyre.
- William Cecil Bosanquet
- Date:
- 1909
Licence: In copyright
Credit: Serums, vaccines and toxines in treatment and diagnosis / by Wm. Cecil Bosanquet ... and John W.H. Eyre. Source: Wellcome Collection.
331/378 page 319
![MALTA ELVER 310 or 1 : 100 of a serum which fails to agglutinate the coccus in dilutions of 1 : 10 and 1 : 20. Serum treatment.—Wright and Semple 1 have treated one case of this disease with a curative serum. The mode of preparation of this is not stated, nor can trial in a single case afford any trustworthy evidence of the value of the remedy. Eyre 3 also prepared a serum from a horse, which agglutinated in dilutions of 1 : 3,000 to 1 : 5,000, and had some prophylactic power ; but it did not prove very effec- tive as a remedy for the disease. Vaccine-treatment.—Reid3 used therapeutic inocu- lations, controlled by estimations of the opsonin-index, as a mode of treatment, with good results. Bassett-Smith4 also prepared a vaccine by heating agar-cultures of the micro- coccus to 60° C. for half an hour, but did not find it efficacious in the treatment of the disease. Eyre5 employed similar vaccines for prophylaxis, and considered that some protection was thereby afforded. AFFECTIONS DUE TO BACILLUS COLI COMMUNIS The Bacillus coli communis is a normal inhabitant of the human intestine. Under certain circumstances, such as constriction of the gut, injury to the peritoneum, per- foration of the intestine, Ac., it is capable of giving rise to serious symptoms; it may also be found in suppurative conditions, such as pyelitis and cystitis, otitis media, Ac., in all of which it acts as a pyogenic organism. B. coli may also give rise to a true septicaemia, and is frequently associated with Streptococcus lonc/us in the causation of puerperal septicaemia, thus explaining the occasional failure of antistreptococcic serum to check the course of that infection. ] Lancet, 1899, i. 1024. 1 Hep. Medit. fever Commits., 1907, Parts v.-vi. 3 slnn. Rep. Sanit. Com. with the Gov. nf India for 1905, p. 153. 4 Journ. of H>jg., 1907, vii. 115.](https://iiif.wellcomecollection.org/image/b28072741_0331.jp2/full/800%2C/0/default.jpg)
