Diseases of metabolism and of the blood : animal parasites, toxicology / ed. by Richard C. Cabot ... An authorized translation from "Die deutsche klinik" under the general editorial supervision of Julius L. Salinger, M. D. With one colored plate and fifty-eight illustrations in the text.

Richard Clarke Cabot

Date:: 1906

Credit: Diseases of metabolism and of the blood : animal parasites, toxicology / ed. by Richard C. Cabot ... An authorized translation from "Die deutsche klinik" under the general editorial supervision of Julius L. Salinger, M. D. With one colored plate and fifty-eight illustrations in the text. Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

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$Except in the cases just mentioned a decided diminution in the absorption of fat. e. g., as a result of disturbance of the gastric chemism, has not yet been observed. With insufficient or increased HCl in the gastric juice, and also in complete achylia (apepsia), the fat appearing in the feces does not amount to more, or to but very little more, than the usual percent;!.:''. On the other hand, unusually large amounts of fat are found in the dis- charges in disease of the intestine (amyloid degeneration,1 talus mesenterica,2 chronic intestinal tuberculosis with chronic tubercular peritonitis.3 fatty diar- rhea [Biedert4]). Regarding the laws of albumin ahsorption in the sick, y. Noorden6 has demonstrated the surprising fact that the absence of HCl in the gastric juice, in spite of its great importance for the peptonizing of the albumin bodies which is necessary for their absorption, nowise influences the assimilation of the latter. Patients with disease of the stomach, with anacidity and with hyperacidity, showed a quite normal power of albumin absorption in the intestine. But later, in cases of apepsia gastrica8 and of pernicious anemia7 in which not only HCl but also the digestive ferments of the gastric juice were absent, slight diminution in the absorption of albumin was observed. It must, however, lie remembered that in these conditions there is often not only independent disease of the mucous membrane of the stomach, but (as the anatomical Undings in individual cases have also shown ) actual atrophy of the glands in the intestinal mucous membrane. Hence it is easily undersl 1 how, in the absence of any peptic effect upon the albumin in the stomach, the vicarious intestinal digestion which ordinarily occurs does nut produce complete absorption. The Blight albumin losses in the feces, which amount to from 11 per cent, to 15 per cent., instead of 7 per cent, as in health, in these cases and also in complete occlusion of bile from the intestinal «anal, are in sharp contrasi with tin' great losses which occur in occlusion of the pancreatic juice (Deucher, Weint raud. loc. cil. ) . In extensive disease of the intestinal mucous membrane (as in an atropine nursling),8 in intestinal amyloid disease, in extensive intestinal tuberculosis10 greai losses of nitrogen have been observed in the feces. i /';-. Müller, loc. cit. - Ail. Schmidt, loc. cit. 3 Weintraud, Ute. cit. * Biedert, Jahrbuch der Kinderheilkunde, Bd. xxviii, p. 21. ■'•/'. Voorden, Die Ausnutzung dor Nahrung bei Magenkranken. Zeitechr. f. Min. Med., Nr. 17. p. 137. o Strauss, Untersuchungen über die Resorption und den Stoffwechsel l><i Apepsia gastrica. Zeit sehr. f. klin. I//.. I'd. \li. p. 280. tErben und Steyskol, Klinisch-chemische Studien. '/> it sehr, f. klin. Med., Bd. \1. p. lti.).— Morozevoski, Stoffwechselversuche l»i schweren Anämien. Vtrchovts Archiv, Bd. clix, II. ft 2. Rubner und Eeubner, Die künstliche Ernährung eines normalen und eines atro- phischen Säuglings. ZeiUchr. f. Biologie, Bd. xxxviii, p. 315. ■ Müller, loc. oit. lu W'cintraud, loc. cit.$