Diseases of metabolism and of the blood : animal parasites, toxicology / ed. by Richard C. Cabot ... An authorized translation from "Die deutsche klinik" under the general editorial supervision of Julius L. Salinger, M. D. With one colored plate and fifty-eight illustrations in the text.

  • Richard Clarke Cabot
Date:
1906
Catalogue details

Licence: Public Domain Mark

Credit: Diseases of metabolism and of the blood : animal parasites, toxicology / ed. by Richard C. Cabot ... An authorized translation from "Die deutsche klinik" under the general editorial supervision of Julius L. Salinger, M. D. With one colored plate and fifty-eight illustrations in the text. Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

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    the nervous system. Meat and egg* are withdrawn and the patients are put upon a vegetable diet. To this no special objection can be raised, provided it is carefully chosen; but too frequently it is lacking in nourishment. This lias been so abundantly proven as to need no further consideration at this point. 4. OCCURRENCE AND CONSEQUENCES OF OVER-NUTRITION If the food (i. e., its combustion value) exceeds what is necessary for maintenance we have the condition of hypernutrition. In over-nutrition the organism does not increase its processes of combustion, or, at least, does so to a very slight extent. Perhaps the increase of oxidation which arises from over-nutrition has been for a time underestimated, as the latesi investiga- tions of Fr. Müller appear to prove. Theoretically this increase is interest- ing, but it is too slight to be of practical importance. The increase of oxidation is not due to a stimulation of the cells to a greater katabolic activity, in other words, to a greater rapidity of metabolism, but only to the greater labor which is put forth by the mechanism of mastication, the stomach and intestines, the digestive glands, the organs of circulation and respiration, etc., in order to work up and utilize the greater mass of food. After deducting the slight amounts spent upon the increased labor of diges- tion, etc. (about T per cent, to 20 per cent, of the energy supplied by the food), a large residue from the superfluous food remains, which accumulates as reserve material, and serves to increase the body mass. We call this food surplus'' (= the difference between food ingested and food used up in metab- olism). Aside from slight differences it is of no importance to the processes of metabolism whether the surplus of food occurs from excess of albuminates or of N-free food, or whether the increased supply come- from one source only (the albumin or the I'at or the carbohydrates). A surplus of carbohydrate nourishment favors almost exclusively the production of adipose tissue, pro- dded special circumstances do no! promote the increase of protoplasm (see above). In an especial case (B. K rug's experiment upon himself carried out under my direction) the following calculations were made: Dr. Krug (perfectly well and in a moderately good state of nutrition), after a period in which he had been abundantly nourished, took for fifteen days in addition to his ordinary food a daily total of 1,710 calories, consisting of fat and carbohydrates. This sum represented surplus nourishment; for the fifteen days it amounted to 25,650 calories, of these 23,05] calories were utilized by the body. 1,720 calories = 7.46 per cent, albumin accumulation, and 21,331 calories: 92.54 per cent, accumulation of fat. Whether the production of albumin was equivalent to accumulation of flesh Could n<>t he decided. It follows from the preceding statements that after the ingestion of a surplus amount of food only an accumulation of fat can certainly be counted