The pathology of tuberculous bone / by Cornelius Black.
- Black, Cornelius, 1822-1887.
- Date:
- 1859
Licence: Public Domain Mark
Credit: The pathology of tuberculous bone / by Cornelius Black. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![MKAN DIAMliTERS OF THE OSSEOUS WALES OF TUBERCULOUS BONE IN THE a b c d e f 9 h i 3 k I m n 0 P <1 r s t ULCERATIVE STAGE. H 3- i 2 4.1 3 4- i 4-i 3 3 3 5 5 2.1 5 4^ 4 A H 78 Mean average, inch. Whilst the destruction of the walls of the cancelli is progressing, as above shown, the exudation within the cancelli themselves, unable, from the absence of the circulation, to derive the pabulum of nutrition for its perfect development into cells, undergoes fatty degeneration. Hence, the microscopic examination of bone, which has undergone these pathological changes, shows partial or com- plete destruction of the walls of the cancelli (Figure VII.); whilst the contents of such cancelli consist of oil-globules of various sizes from a metamorphosis of a portion of the exudation, masses of ex- udation-matter more or less converted into fat, granular matter and patches of the lining membrane of the cancelli in a similar con- dition, together with the ultimate earthy particles of disintegrated bone (Figure Y.). As the deposit of tuberculous matter is not of equal amount throughout the affected cancelli, so neither does the process of ulceration in them observe the same period of time or the same ratio. The greater the amount of exudation within the cancelli, and the nearer this is to the source of vascular supply, the sooner does ulceration take place. Hence, the surface of a short bone, and next to this, in a long bone, the immediate neighbourhood of the termination of the medullary canal, are the seats at which ulceration, in tuberculosis of bone, first occurs. In the former, exudation into the superjacent soft parts, and its subsequent germination, growth, and degeneration, constitute abscesses, which open a communication between the surface and the diseased bone. In the latter, this condition of the su]>erjacent soft parts ma}' not occur until the exudation in the cancelli, near the termination of](https://iiif.wellcomecollection.org/image/b22342588_0030.jp2/full/800%2C/0/default.jpg)


