Bovine tuberculosis in man : an account of the pathology of suspected cases / by Charles Creighton.
- Charles Creighton
- Date:
- 1881
Licence: Public Domain Mark
Credit: Bovine tuberculosis in man : an account of the pathology of suspected cases / by Charles Creighton. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![to other aniumU by ex|>eriiiieiit. Trolongwi fet-sUn^ witli the milk of u tuberculuiLS cow, or with the uctual jM.nirl'tio<lule«, hiu» Hutliccil to Het up a correa{K)iuling diu^ae in the ailf, lamb, goat, pig, and rabbit. The induced diaeuae differs from the original diseaiH) of the cow in the im|M>rtant reajiect thut the foniier U a somewhat acute infective process, where^as the latter, gonerally inherited, is of slow development Corresponding to this difference in the intensity of the process, the morbid pro- ducts in the casus of induced {>enrl-<lisea8c are not (|uita the same as in the indigenous Isivine disease. They are not quite the same, but the identities of form and struclure are suflicicntly striking. Thus, although the serous membranes an;, in the infucte<l animals, seldom or never covensl by |M*ndulous nodules or conglunierat4*M of noduh'S, they will bo found on closo exa- mination to show* traces of those soft vascular villous-like out- grow'ths which an> known to be the early stage of the nodular fonnationa To use the convenient expression of Gcrlach, they show “the l>eginningM of I’erlsucliL The cxj»eriments which Orth nuide with rabbits did not result in prtKlucing a disease identical in every i>oint with that of the cow's from which the infecting material was taken; but the resemblance w*as suffi- ciently close to leail Orth to s]>eak of the disease induced in the rabbit ns “ Kaninchen-rerlsucht.” In jmrticular, the micro- scopic structure is the same, and, on the cnicial point of the vascularity of the new growth, Oerlach hiw notetl a certain amount of evidence of identity. The implication of the lym- phatic glands, also, is practically the same in the experiment- animals as in the cow. It is not diflicult to suggest the reason why the induced disease as a whole is somewhat unlike the parent disease. In the disease communicated by the feeding ex|)eriments, the morbid process in the lungs seems to take ])recedence, owing to the mode of entrance of the vims, over that on the serous membranes. The latter is no longer the chief feature of the disease, but what there is of it is characteristic enough. There is little doubt that the pearl-disease, modified only in the relative development of the process in the various organs, has been communicated to animals by experiment. There is evidence, also, that it has been communicated to animals by I](https://iiif.wellcomecollection.org/image/b2226758x_0114.jp2/full/800%2C/0/default.jpg)
