Bovine tuberculosis in man : an account of the pathology of suspected cases / by Charles Creighton.
- Charles Creighton
- Date:
- 1881
Licence: Public Domain Mark
Credit: Bovine tuberculosis in man : an account of the pathology of suspected cases / by Charles Creighton. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![value. I Iluve iutroduced aii account of the experiments ami ohMervutiouM of Urtli in ('hupterH VI. and following. The |>a{ier by fierlach, from which 1 hIiuU «|uoto somewhat fr»?ely,* usiii{' iUdit* where iiect^Msury, reconls two c)osm*s of ex- }>erimenU, the first beiii); a series of ei<{ht inoculations under the skin of nodules from the <’ow, and the second a series of ei^ht feediii({ ex{Mrriinents with the nodules or with the milk of the animal. I shall quote one of the fonner class, and tliree (wholly or }Mirtially) of such of the latter ns refer to ftMalinp; with milk. Hefon* doiii|{ so, I shall <|Uote the facts relating to a tuberculous cow which furnishcHl the material for several of the cx)>crimeuts. A cow, seven to eight ymrs ohl, was procunNl for the purpnsu of tho ox|)vriiu«’iits. Till* animal woswosUhI, hail difllcult bn'alhing and cough. ItAlcM in the rhost were audible, but there was tin dtilneM. Fever hail not yet sot in, and the ap|M;tiU< was goutl. Thu daily yield of milk was lAOO gratmnosL Killnl after threo months; during that interval tho wasting had increased, and the amount of milk hu<l laKromn lues (during the first month tho doily average was COO gremmus, during tho second month 500 grammes, and during the lost eight days it was almost absent, the animal being widl ^*<1 all the time). Piml-nwrtrm,—I*orictal, diaphragmatic, and mediastinal pleura covered with innumerable smooth glancing mslulcs fnmi size of lentil to tliat of ]>ea ; tho pulmonary pleura more siianudy stuiidud with liodulos. There wore present no conglomemtos of noilulos nor grape- like mosses on tho serous nicnibranos. Tho lungs were voluminous and of doublo tho usual weight On handling them, they felt normally clastic in some parts, and in other parts firm and nodular. Tho bronchial glands wore remarkably enlarged, hard and nodulated to thu feel, and creaking under tho knife. On the cut surface of tho lung, a considerable amount of destructive change—small and largo cavities, some with muco-punilent, others with caseous contents, and with thick tnnooth walls ; also miliary tubercles from size of a mere visible j»oint to that of millet seed, partly scatteroii and jMirtly aggregatwl together. Commenting aftcrw’nrds on this ca.se, he observes— It is quite usual to find destnictive changes in the lungs in Perlsucht, liesides the nodules on the serous membranes. I have never found the nodules of Perhucht associated with sound lungs and normal bronchial glands. In the lungs I have found either • A. C. Oerlach, “ Uelwr die Impfh«rko.it der Tubercnlose und der Porlsucht bci Thierp, aowie Ul>er die UelsTtragiiarkeit der lelrteren diirch Kiittenmg” (Aunziig su» detn .lahreslwricht der K. Thierarznei-Schulc zu Hannover, 18G9, S. 12/-151). —Virchow’s Archir, vol. li. (18/0) p. 290.](https://iiif.wellcomecollection.org/image/b2226758x_0036.jp2/full/800%2C/0/default.jpg)
