Bovine tuberculosis in man : an account of the pathology of suspected cases / by Charles Creighton.
- Charles Creighton
- Date:
- 1881
Licence: Public Domain Mark
Credit: Bovine tuberculosis in man : an account of the pathology of suspected cases / by Charles Creighton. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![)iuii«lrrtl lUjrv from iho comiimii<'<«mc>iit, nml Hfty day* afUT the end of the fixMliu^ ox|»«'riimmt, the calf wax killtxl for anutoiuicai |iur{»oik^. /‘tml nu/rtnn.— (1) The pleura over the jjnmter |Mirt of the aharp l>or«ler of the right lung wax covere*! with iMtcatr, rf<l fUamriilotui exerrseruees, tehtfh huntj like o /mt^e uImhI one rrnlimrfre ucrr the lutif/ morj/iN, at certain phtcea lading unit«<l like a meiiihnme, ami in •ome ploceii containing glancing pin-head n<Mlulea; the parietal pleura at varioua |Miinla cover»«l with delicate lilainetiloua new forma- tiono, nch in ve*aeU. (2) The lunga allowed a variety of nodulee, hut were otherwioii lionuoL Inmietltately tielieath the pleimt, and pro- jecting more or hwa, lay four mxltih** the aire of fxaui, and «ix ikmIuIoi the aize of millet oeoda, and in the lonoe interlobular conm*ctive tiiwue there were eight miliary iiodulea. The mnall nodiilea wen* the moro tranaluc4*nt; all wen* grey in colour and of linn texture (amall deliraito new-gniwtlia); the cut aurfoce ahow«*<l oeveral clear |KiinU; in one of the Urg*'r nodiilea a yellow cheeay mooM lay in the centre. (3) linmrhinl glnmis all much awollen, amf occupie<i in their inlx*rior with numemua pin-luaul mjce«l purulent and coMynia centnw, which hem and them contained calnan-oua matt4*r; thew tulH*rcIo-centn*a atoo<l out Very ronapiciioualy on oection. (4) J/ram/rnV glomh all much awi>llen, aiul in plocea n(Mlulat«<l on the ourfoi’e, of the si/e of walniita, the half next the inteatino being moat awollen. The o<*ction allowed, ca{>ecially in the notlulatinl enlargemento, the ^ame pictum, but pmro pnmounceil, oa in the bnmchial glando. All fheee tliaeaeed glawh were ejntrlly like the reeenily afeeletl lyntfthalie glamU in /‘rrUueht of the row, Kxp. 13. An eight-month's lamb, fed with milk fmm the same cow, kille«l aft4*r three* months. Among oUier jxml-nufrlmi a]i|>enninc4fa (chiefly ornittiHl]; on the ahaqi margin of each lung a patch of nt<dccta*«is the size of a ahilling, in which was situated a mnlule tho si»* of a b«>«n, abruptly boumb*<l, of grey colour and medullary con- sisU'nco on section. On microscopic examination, giant-cells were miKiH>il from tho alxive nodules, but they contained capillary vessels distendeil with blootl-corjmscles. Kxp. 14. A pig, six to eight weeks old, was fed for twelve days with milk (400 grammes daily) from the same tuberculous cow. It was killed thirty days after the end of tho fee<ling exjieriment. Poel-mortrm.—(1) The whole lower sharp margin of tho right lung was occupied in some places with a border, in other places w’ith a fringe ; i.e., the pleura pmsente<l a constricted thickening, composed of filamentous excrescences of 2 mm. diameter and up to 1 cm. in length ; the filamentous out-growths contaimHl clear pin-head iumIuIcs gnrrounilrd hy a wreath of (tUteiulrd l>lo<t<la'rg$rle. On dijiping tho lunga into water, these new formations showed to best advantage. (2) In the right lung, middle lobe and parts next mediastinum, w'ere found grey-coloured nodules, tho size of a walnut; they lay under tho [iloura, which here an<I rouml aliout was coven*d with nnl villi, rich in vessels; near these nodules, there lay several clear grey miliary nodules, snrroumicd by a cirrlrt of ilielctvh’tl Nood-vrwele. On](https://iiif.wellcomecollection.org/image/b2226758x_0038.jp2/full/800%2C/0/default.jpg)
