Bovine tuberculosis in man : an account of the pathology of suspected cases / by Charles Creighton.
- Charles Creighton
- Date:
- 1881
Licence: Public Domain Mark
Credit: Bovine tuberculosis in man : an account of the pathology of suspected cases / by Charles Creighton. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![wliLMi first HtHJii, tlio iii(yiulltir)’ whitom*'^ of a stHroiuiary tumour, l»ut it wiim at the Maine time iimre o|HU|tie, yellowiali or f*rey. The microscopic drawinjj;s on I’late IV. im* both made from the Hume W(*<i^c-Mha|MMl nodule. With the naktMl eye, one can see that it is ma»le up of the confluence of •evend round nodules, and thestj, apiin, n*solve themselv(‘s under the microMCo|>e into many Mtiiali tulK'tvles, The tuliercles art* iiiterHtitiul formations in the connective tissue of the lun^ ; they have a U*ndcncy to necrosis in the contn*, the iu*crotic and sometinnst softencHl centre hreakin({ away, by a very unihirm mar- jfiti. from the {frowin^ and vascular |»eriphery (tij(. 11, Tlate IV.) The ctmtnil tulM*rcle of the same fij^iit* shows a numlM*r of {^iant* cells, and vesstds [M*netratiii){ into the ccntn* of it 1'he tul>ertde of ti{{. 12 (Plato I\'.) rt*pn<«ents a very usual and characteristic ap|M*antnce; the mslule is suirounded by a remarkable wrt*nlh or circlet of wide IiUmmI*vessels of capillary stnicture, diKUmd(*<l w'ith blood; a small vessel ]>asst!s rit'ht through the sulistancu of the tulien le, ami several others are found in its latriphery. To the nakt*d eye, the smaller wdiitish no<lules that occurred throughout the right lung had a }H*culiarity which I shall have often to refer to; on the cut surface, they appeartal sometimes to lx* jK'rfomted with a narrow lumen, the npjK*arancc suggest- ing the broken stem of a clay pijxi or a piece of macaroni; at other times, the section showc<l them to l)e hemispherical Ixslies with the centre excavated to a limited extent, and w'ith a sub- stantial thick wall, the interior Ix'ing uneven. The cnlargeil bronchial glands were found, on microscopic examination, to contain tulsTcles, ns in fig. 14, I’lnte V., from another case. The remarkable appeaninc.c represented in fig. 3, riak^ II. is taken from this case. The whole under surface of tlie diaphragm, on the right side, corresponding to its area of contact with the liver, was covered with that kind of eruption. The tulxjrcles were large and fiat, sometimes jiartly free from the surface, and surrounded by filamentous tissue. E.xamined with tlie micrascope, some were found to consist of several centres of new fomiation, wliile in others the interior had under- gone a general necrasis, and it was only round the iieriphery tliat any structure could be seen. Tlie structure is that of fig. 15, I’late VI., from another case. It is the tubercle composed of](https://iiif.wellcomecollection.org/image/b2226758x_0044.jp2/full/800%2C/0/default.jpg)
