A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.
- Timothy Richards Lewis
- Date:
- 1872
Licence: Public Domain Mark
Credit: A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.
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![[ I J' ] resembling tlicse arc, more or less, generally found in all intestinal discharges, and arc probably the result of cndos- motic processes acting on the epithelial cells, as was long ago pointed out by lleidenhain and Briicke in connection with appearances observed in healthy epithelium; they may occasionally be seen closely attached to the cells in tliosc very exceptional cases in whicli epithelium can be detected in choleraic discharges, as well as very frequently in con- nection with the loose epithelium found in the intestines after death, as figured and descriljed in the last report.* These observations on the blood, especially when taken in connection with the light which they throw on the nature of the cells and bioplasts of the evacuations, do not tend to indicate the presence of a microscopically demon- strable morbid poison in either medium, tliey merely show that the escape of materials from the blood is sufficient to account for the presence of the most remarkable and con- stant microscopic features in the evacuations. B.—Results of microscopic examinations of the blood in health and in diseases other than cholera. As miglit be supposed, these systematic observations ^ . ^ on the blood in cholera were not Preliminary observations -■ •ii i i • were^ made with normal Commenced WltUOUt OUT iiaVlUg, aS we thought, made ourselves practi- cally conversant with all the changes discernible in normal blood; indeed, on referring to our notes, we find that daily, and in several cases hourly, observations had been entered relative to about three dozen specimens examined in pre- cisely the same manner as the foregoing, but in none of tliem is there any allusion to the phenomena just described. Whereas in the written description of the second case of the cliolera-blood series, we find it entered on the fourth day that the serous portion of the specimen is crowded with granular, white corpuscles, extremely like pus-cells. Then follow careful notes of between sixty and seventy specimens in which the various stages above summarised are minutely described. Thinking that it might by no means be impossible that similar changes might have been The changes occurring in i i i • it ^ ^ t ^ normaland cholera blood are, OVCrlOOKed lU the nomiai OlOOd SCl'lCS, to a certain extent, identical. , • i j. ^ i • i we determined to go over this ground * Sfiventh Annual Report of the Sauitary Commissioner witb the Government of India : Appendix B, Plate III.](https://iiif.wellcomecollection.org/image/b20392023_0024.jp2/full/800%2C/0/default.jpg)
