A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.
- Timothy Richards Lewis
- Date:
- 1872
Licence: Public Domain Mark
Credit: A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.
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![lower end of the ileum, just above the unaffected portion of the mucous membrane, the separation of the epithelium was not so far advanced as higher up, and appeared to be m a state of transition towards such a condition. The mesenteric glands were highly congested internally, . ^ of a soft consistence, and contained bSfa*'^'ateb^^^^^^ an abundance of pink fluid. A pre- paration of this fluid was mounted as usual in a wax-cell. When examined an hom^ and a half subsequently, it was found to contain an abundance of minute bacteria, a sprink- ling of the long vibriones occurring in the glands and intes- tines of the previous case, together with normal gland-cells and numerous red blood-corpuscles. Sixteen hours later, it contained an abundance of minute active bacteria, together with molecular matter, fatty crystals and cells, but showed none of the elongated vibriones previously present m it. The large intestine and appendix vermiformis were Laxge intestine Healthy. uormal in aspcct, and the rest of ^ the abdominal viscera appeared healthy. The bladder contained a little urine. On openino' the thorax there were found to be numerous cancerous nodules ttrongh. krgC CanCCrOUS nodulcS thrOUghout out tlie lungs; slight pencar- ^-^^ SubstaUCC of both lUUgS, WhlCh were collapsed, but Contained a little air. There was slight inflammation of the parietal pericardium, and the visceral layer also was somewhat injected. A preparation of blood was, as usual, procured from the right ventricle and mounted in a wax-cell. When examined about two hours afterwards, the serum was found to be deeply ^ . - ^ , . ■ ^-^ stained with the colouring matter of Bacteria developed m the iai't-fj--'^'-'- o . blood. i]^Q red corpuscles, and to contam numerous minute active particles, but no distinct bacteria could be detected in it. Sixteen hours afterwards it was crowded with large blood-crystals and contained an abun- dance of minute active bacteria. Experiment X.—A small healthy pariah dog having Material used, same as in been put under the influence of chloro- Ss'Sd.^'' ^i-ix., 80 fo^,^^ about three di-achms of the same fluid employed in the three preceding experiments, but which had now been kept for nearly eight hours longer, was injected into the right femoral vein. Death in about 6 hours. rJ^^^ injectiou was performed at 4 p. m., and the animal died during the night. A post-mortem exami- nation was performed at 7 a. m. of the following day.](https://iiif.wellcomecollection.org/image/b20392023_0045.jp2/full/800%2C/0/default.jpg)
