A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.
- Timothy Richards Lewis
- Date:
- 1872
Licence: Public Domain Mark
Credit: A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.
49/126 page 39
![ExPEUiMENT XIII.-A healthy pup was put under . chloroform, and three drachms oi se^mfrjS^dl^o^^ioid:''^^ cholcraic material injected into the left femoral vein. The material consisted of the fluid and sediment of an evacuation thoroughly shaken up, and was in an active state of decomposition, the fluid bemg covered with a thick layer of bacteria, and the sediment consisting m o-reater part of amorphous matter with a few persistent red blood corpuscles. The injection was performed at 9 a m., and the dog rapidly came out of the influence of the chloro- form. It died at midnight of the Death in about 15 hours. game day without having shown any choleraic symptoms. A post-mortem examination was performed at 8 a. m. of the following morning, 23 hours after the operation. Hh^post- mortem rigidity was well marked. Post-mortem appearances. rpiie]>e ^as uo cvidencc of inflamma- tory action around the wound in the thigh, which appeared clean and healthy. On opening the abdomen, the cavity was found to be free of fluid, the surface of the small intes- tines appeared slightly roughened, but the parietal peri- toneum was perfectly smooth and glistening, and there was no evidence of inflammatory action present. The stomach was empty, and there were a few A few ecchymosed spots in ecchvmoscd spots on the mucous jejunum and the ileum coated J mi i i with reddish mucus. mcmbranc. The duodenum ap- peared healthy and contained a small quantity of bile-stained mucus. The mucous membrane was perfectly free of injection throughout the upper portion of the jejunum, but towards the lower extremity there was an ecchymosed patch three or four inches in length. The ileum contained an abundance of mucus of a peculiar reddish hue. The large intestine was also coated with abundant reddish mucus. The liver both on the surface and throughout its sub- stance showed numerous small, light teg?kt'd mat er ti^ou^S colourcd spots about the size of Small the liver. shot. There were no inflammatory rings around them; after the specimen had been for 12 hours in a weak solution of spirit, these spots, where on the sur- face, appeared slightly prominent; but these prominences disappeared on exposure to the air, and slight depressions replaced them, appearing to indicate that they had been due to an abnormal absorption of fluid at these points. On mi- croscopic examination, the material composing these light](https://iiif.wellcomecollection.org/image/b20392023_0049.jp2/full/800%2C/0/default.jpg)
