A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.
- Timothy Richards Lewis
- Date:
- 1872
Licence: Public Domain Mark
Credit: A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.
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![L ] of cylindrical epithelium mixed with ahundance of bacteria and vibriones. The liver was yariegated with light, yellow- ish, fatty spots. It contained no evidences of embolism. The kidneys and spleen were perfectly healthy. The bladder was empty. The pleural cavities were healthy, and the lunes were collapsed, pale and devoid ■moracic cavity. Wo active J-LiJJ.t,'=vv 1 i' 1- ^ mu^ v.r. bacteria ia blood when re- g^j^V traCCS of embollSm. ihe pC- moved from the heart, but J. rvu^ numerous motionless parti- ncardlUm WaS QUltO lieaitliy. ±116 cles and abundant active ^^^-^ r, i-r i i. j.„ bacteria subsequently. ri^ht cavitics of thc heart wcrc empty, and the left contained a'^ little fluid blood. Preparations of blood were procured from the heart and from one of the systemic veins. These, when examined a quarter of an hour subsequently, showed no active bacteria, but a uniform sprinkUng of minute motionless particles throughout the serum. Twenty-four hours subsequently the preparations were crowded with active bacteria. Experiment XVIII.—This experiment was performed at the same time and with the same flSSho'urs'oTp^ect^^^^^ material as the preceding one. A ly as in the last experiment. ^^^^^ Wealthy dog haviug bcCn put under the influence of chloroform, four drachms of the fluid was injected into the right brachial vein. In consequence of a failure in the first attempt at injection and of the subsequent slip- dSSg'the^operatfon°and ex- pinff of a ligaturc, the animal was treme depression afterwards; i^^^^ ^^^^ ^^^^ ^.^^ ^^^^^ chloroform, and moreover lost a considerable quantity of blood. The operation was at length, however, successfully performed. The dog seemed to be much depressed and whined as though in pain for some time. Dming the night, however, he improved greatly and drank some water; and on the follow- but the dog recovered com- . • i i. i i i „ pietely in a few days and was lUg mommg hC atC ancl ClranK grCC- set at liberty. and scemcd to suffer more from stiffness of the wounded limb than from any constitutional symptoms. The wound looked clean and healthy, and the animal was bright and lively in appearance. He continued free from any constitutional symptoms, and five days after the operation was set at liberty in full health and excellent spuits. Experiment XIX.—A pariah dog of average size put Material used (supernatant Under thc iufluencc of chloroform at fluid). 96 hours old. ^ r^^^ f^^y, drachms of the](https://iiif.wellcomecollection.org/image/b20392023_0055.jp2/full/800%2C/0/default.jpg)


