A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.

Timothy Richards Lewis

Date:: 1872

Credit: A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.

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$opposite the most purplish portions of the intestine. The pinkisli tint of tlie contents did not, in this instance, corres- l)()iid with the presence of patclies of worms, for tlie latter were in^ several instances ohservcd to occupy pale portions of the intestine. The liver was healthy; the kidneys were congested. The pleural cavities contained no fluid. The lungs were Blood from the heart con- collapscd, airlcss and ])l()odless. Both tained monads and bacteria. gjj^g ^^^.^^^ y^^^^^j^ The hlood contained active monads and distinct bacteria. 0*-)—Choleraic material used being eighteen days old. Experiment XXX.—A very young pup, similar to that employed in the previous experiment, was put under chloro- form, and nearly one drachm of the same evacuation, w4iich had now been kept for 18 days, was injected into the right femoral vein. The operation was performed without loss of blood; although respiration ceased, it was readily re-estab- lished, the restoration being apparently facilitated by holding the animal up by the heels. There were no symptoms of intestinal affection, but death supervened ten hours subse- quent to the operation. {k.)—CJioleraic material being nineteen days old. Experiment XXXI.—A healthy dog of average size Injected material 19 days WaS put Uudor tho influence of old; the dog weu in two days, chloroform, and four diachms of the same evacuation employed in the previous experiment were injected into the left femoral vein. There was no haemorr- hage, nor were the surrounding tissues disturbed. Towards ' the close of the operation the respiration became imperfect, but it never fairly ceased, and the animal quickly recovered from the effects of the chloroform. It did not appear to suffer from the operation, and in two days appeared to be in perfect health. Experiment XXXII.—A healthy pup was put under Injected material 19 days ^10 influence of chloroform, and a few old: death in 5 hours. drachms of the supcrnataut fluid of an evacuation which had remained for 19 days in the laboratory was injected into the right femoral vein. There was hardly any heemorrhage during the operation, and the dog rapidly recovered from the influence of the chloroform.$