A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.
- Timothy Richards Lewis
- Date:
- 1872
Licence: Public Domain Mark
Credit: A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.
84/126 page 74
![[ 71. ] aspect as at tlio lower end of the ileum, or deeply blood- stained and tarry as furtlier up. The liver was dark in colour and very full of blood, but Bemnining abdominal via- ^o farther change could bc detected oerahealthy. -j.^ rj«|jg remaining abdominal or- gans AA'cre congested, but no special lesion could be detected in any of them. The bladder was full of urine. On opening the thorax, the pleural cavities were found to be free from fluid. The lungs Thoracic viscera healthy. collapSCd and healthy iu tCXturC. The heart was healthy, the right cavities full, but not distended with fluid blood, and the left auricle and ventricle cmpt3^ • A preparation of blood from the right side of the heart was mounted in a wax-cell and set i>ZTtroltSeZTt'^eAstt aside for further examination, along ^^^^^ with the preparation procured previous to the operation. Both preparations were examined on the following morning at 9 A. m., when the one had been kept for above 24 and the other for about 14 hours. On exami- nation the former was found to be quite free from bacteria, and to contain very abundant bioplasts in the pus-lil^e condi- tion previously alluded to, whilst the ■when examined on the , , i Tnn i j? • j-1 following day, were crowded latter Only diiiered irom It m tuere with pus-iike corpuscles, but ^^^j^^g ^^^^^^^r fcwcr biopksts free in the serum. They were again carefully examined two days subsequently. They both remained very fluid in consistence, very few bioplasts were present in a distinctly defined con- dition, they were aggregated in masses, t^iacoSid^e^seen^nor did and appeared to bc rapidly undergoing they subsequently appear. ^lisintegration. Neither bactciia nor active molecules could be anywhere detected in either prepara- tion. On subsequent examination the only changes observed in either specimen were gradual disintegration and there was no development of bacteria in them. ExPERiMiiNT LXJX.—At 12 noon of the same day in f T, ^ vnvrr^n+P wMch thc prcccding experiment was An ounce of choleraic mate- n i ' ' riai-about 100 hours old, nerformed. chloroiorm was aclmmis- injected into peritoneal cavi- 1-^ ,-, i i ty of a dog. td'cd to auothcr large healthy pauan dog, and about one ounce of the same choleraic material was injected into the peritoneal cavity througli a canula. The dog soon recovered from the primary effects of the](https://iiif.wellcomecollection.org/image/b20392023_0084.jp2/full/800%2C/0/default.jpg)
