A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham.

  • Lewis, T. R. (Timothy Richards), 1841-1886.
Date:
1872
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Licence: Public Domain Mark

Credit: A report of microscopical and physiological researches into the nature of the agent or agents producing cholera / by T.R. Lewis and D.D. Cunningham. Source: Wellcome Collection.

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    very delicate vibriones took place, whilst the preparation was under observation. They were elongated, of extreme tenuity and of great activity. On the following day the serum was swarming with the bodies described f^U^ustiIent?^'S?ir^^^^ above. They remained very active, ^^^^^ and their delicacy was so great as to necessitate most careful management of the light, in order to render them visible. No further development occurred; and the only changes subsequently observed were gradual diminution in the activity of the vibriones together with breaking up of the small number of white cells present in the serum. Experiment LXXIV.—Whilst ihe post-mortem examin- ation described in the previous expe- eat flSecteliStrthfab- rimcut was bciug performed, a syringe dominai cavity. ^j^^^ q^^^ Contained in the peritoneal cavity, and another powerful pariah having been subjected to the influence of chloroform, about one ounce of this fluid was injected into the abdomen. During the operation, respiration and circulation ceased for a short time, but tliey were easUy re-estab- Death in 5 hours. Ushcd, and the dog rapidly recovered from the influence of the chloroform. At first, it appeared to be very little affected by the injection; but it rapidly passed into a state of extreme depression, and died five hours after the operation. A post-mortem examination was performed two hours after death, with the following re- pe^r?tonXv^^SedT^'= si^lts. Rigor Mortis had just begun to set in, but the tissues were still warm. On opening the abdomen, there was found to be very marked peritonitis. There was a large quantity of red fluid in the abdominal cavity. When a preparation of this fluid mounted in a wax-cell, blood contained active bac- was cxamincd an hour after its re- Sf6ke^orpus^cit'ald*oii? Hioval from the body, it was found globules. ]3g crowded with minute, slightly moving bacteria and monads, and to contain masses of very small disintegrating pyoid corpuscles, together with numerous free oil-globules. The preparation was kept under observation for several days; but no further developments occurred, and the activity of the bacteria gradually ceased. The intestines were rough and injected externally ; but, when