A manual of chemical physiology : including its points of contact with pathology / by J. L. W. Thudichum.

Date:
1872
Catalogue details

Licence: Public Domain Mark

Credit: A manual of chemical physiology : including its points of contact with pathology / by J. L. W. Thudichum. Source: Wellcome Collection.

Provider: This material has been provided by the Royal College of Physicians of Edinburgh. The original may be consulted at the Royal College of Physicians of Edinburgh.

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    producible from sucli; while tbe other compound acid yields as the second product of its cleavage glykokoll or amido-acetic acid (C3H5]Si02), which is producible artificially by various processes. The rational con- stitution of the smaller nuclei is thus shown to be well known; but the same could not be said of cholic acid. Glykokoll appears in an excretion as hippuric acid (in which it is coupled with benzoic) but it is at present uncertain whether this excreted glykokoll has previously taken any share in the composition of bile or not. Taurine, however, is consumed in the body, and its sulphur appears in the excretion as sulphuric acid. The coloured ingredients of bile are cholopha3ine or bihrubine, C0HyNO2, and bilifuscine, probably C9HnN03. By oxydation and loss of carbonic acid cholophgeine easily passes into biliverdine, CsH;)X02, according to the formula, C9H9N03 + 20 = C8H9N03 + C02. Cholesterine (C26H440) occurring in the brain and blood is no doubt excreted by means of the bile. It is a polydynamic alcohol, capable of forming ethers analogous to fats. Coloured matters, such as cholo- nematine, boviprasine, fuscopittine, muscoprasine, and ethochlorine, all possessing characteristic pro- perties and spectra, and cholesterine are the main residues of certain diseased processes which terminate in the production of calculi. In a degeneration of the liver, called bacony, considerable quantities of chole- sterine remain stagnant in the parenchyma of that oro'an. The choline of the bile is an organic base of