Physiological and pharmacological studies of the ureter ...

  • Lucas, Daniel Ralph.
Date:
1908
Catalogue details

Licence: Public Domain Mark

Credit: Physiological and pharmacological studies of the ureter ... Source: Wellcome Collection.

Provider: This material has been provided by the Augustus C. Long Health Sciences Library at Columbia University and Columbia University Libraries/Information Services, through the Medical Heritage Library. The original may be consulted at the the Augustus C. Long Health Sciences Library at Columbia University and Columbia University.

    17/48 (page 255)
    usually became neutral, the curves often entirely disappearing, the phenomena recurring again and again, tending to become more fre- quent ; but recurrence was by no means regular. Quite often the large ureteral curves were not accompanied by the large pelvic curves. fflY^Wl ~M~~*~~~»*Y^™M~'—\r\r^*~~ Figure 4. Continuation of Fig. 3, thirty minutes later. Lower line, base line- Second tracing from bottom, from straight portion of the ureter. Upper tracing, from renal pelvis. Figure 3. Lowest tracing, time in seconds and base line for the pressure in the straight portion of the ureter. Second tracing, ureter pressure from straight portion. Third tracing represents the base line for the pressure curve of the renal pelvis. Fourth tracing, pressure from renal pelvis. The more rapid oscillations in the pelvic curve do not show in the figure. However, large pelvic curves never appeared under these conditions unaccompanied by decided increase in the size of the ureteral curves, but large pelvic curves could be induced previous to the appearance of, or unaccompanied by, the large curves of the straight portion, by rapidly infusing into a femoral vein 100 to 200 c.c. of warm physiological salt solution. Following the large pelvic curve thus produced, the curves of the straight portion, as a rule, became smaller and more frequent for a time, but subsequently the larger ascents and descents took place again. I am quite sure that the drops in pressure in the straight portion were due to fatigue and relaxation of the ureter; also that the synchronous rises in pres- sure in the pelvic portion, when they occurred, were due to reflux of urine into the renal pelvis, and the return to normal pressure brought about by the recovery and natural peristaltic action of the two portions. When, however, the pressure was maintained or increased, or the action of deleterious agents brought to bear on the ureter, the large curve ra\ in the two portions became higher and the period of n-turn to their previous levels was more prolonged. Subsequently, if the above-mentioned deleterious influences were continued, the