Licence: Public Domain Mark
Credit: Clinical lectures on mental diseases. Source: Wellcome Collection.
Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)
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![bone, which was somewhat softened. The tumour was encysted in the brain matter, but not attached to it, lying quite free in a cup-shaped cavity. The contiguous brain substance was flat- tened out and somewhat softened. The cancerous mass, on microscopic examination, was found to consist of small cells lying in the meshes of a delicate stroma, although much resembling brain matter, but distinguishable from it by the absence of the characteristic larger brain cells of the grey matter. The brain was softened near the tumour, and very anaemic. Abdomen.—There were several small secondary masses of cancer at the pyloric end of stomach, the orifice of which was constricted, I^o secondary cancer in liver, kidneys, glands, or other organs. The splenic artery was enormously tortuous and dilated. Liver was fatty, with thickening of the coats of its arteries and bile ducts, and considerable increase of fibrous tissue round them. The fibrous tissue round the bile ducts was deeply stained with bile even to the smallest duct. Kidneys.—Right kidney full of very large cysts, substance otherwise normal. Left kidney had marked cystic degeneration. The renal substance was almost gone, its place being taken ])y numbers of cysts, many of them containing dark foetid fluid matter. In regard to the duration of each of the distinct diseases, the only guides one has in forming an opinion are the pathological appearances after death. Not one of them pro- duced unequivocal symptoms during life by which they could have been certainly diagnosed, or their course determined. The cystic condition of kidney seemed undoubtedly to have been the first departure from health. But then, on admission, it did not cause albuminuria, oedema, or any other symptoms referable to renal diseases. It was only, in fact, within two months of death that this was so. The contraction at the pyloric orifice of the stomach must have existed some time, l3ut there are no data for saying how long. There is fair reason, however, for connecting this with the loss in flesh, falling](https://iiif.wellcomecollection.org/image/b21270971_0113.jp2/full/800%2C/0/default.jpg)
