An experimental study of bone growth and the spinal bone transplant / Fred H. Albee.
- Fred H. Albee
- Date:
- 1913
Licence: In copyright
Credit: An experimental study of bone growth and the spinal bone transplant / Fred H. Albee. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![as such or acts as an osteoconductive scaffold. This was especially emphasized in the three human cases cut down on. If the graft is to live as such the blood-sup- ply contacts must be of favorable character and numer- ously distributed at short intervals along its whole extent. Such as is the case with the spinal graft or the transplant used for ununited fractures described elsewhere. 3. Ollier in 1858 described his technic for subperio- steal resection, but as far as I am aware, did not empha- size the importance of the employment of a sharp instru- ment with force in order to separate with the periosteum the embryonic layer of active osteogenetic cells, which is situated on the periphery of the compact bone, although it is evident from the description of his work that he frequently practiced this technic. It seems cer- tain that osteogenesis on the part of the healthy peri- osteum removed from a healthy bone, is largely depend- ent on the presence of these active embryonic bone cells from the outer surface of the cortical bone. Therefore the wisdom of the use of the sharp periosteum elevator in bone resection is apparent. 4- The bone transplant apparently acts always as a stimulant to osteogenesis on the part of the bone into which it has been implanted. 5. The spinal graft in the dog loses its identity at about the fourth month. After that time one would not know from its appearance that the bone bridge had originated in this way. 6. Bone taken from another species, such as the sheep, did not unite to the recipient bone of the dog, although m e presence of asepsis. This one experiment does not prove that sheep’s bone will not unite to dog’s bone as a graft, but it does prove the unreliability &of the procedure. J J-Ab°n,e “S6 between different vertebrae was accomplished in this small series of experiments onlv bv snlittZ'S • Breaklng down the spinous processes, the Q *V]nT Processes witb approximation to bridges alff°Uf ?nd the insertion of periosteal bridge! Produce the desired continuous bone thf\,^0Ile i?rans-f^nts taken from a long bone such as when take?°fTom tlideDCe °f S1'Gater osteoSenesis than icumn trom the spinous processes.](https://iiif.wellcomecollection.org/image/b22443654_0017.jp2/full/800%2C/0/default.jpg)
