Medicines, their uses and mode of administration : including a complete conspectus of the three British pharmacopoeias, an account of all the new remedies, and an appendix of formulae / by J. Moore Neligan.
- John Neligan
- Date:
- 1849
Licence: Public Domain Mark
Credit: Medicines, their uses and mode of administration : including a complete conspectus of the three British pharmacopoeias, an account of all the new remedies, and an appendix of formulae / by J. Moore Neligan. Source: Wellcome Collection.
Provider: This material has been provided by the National Library of Medicine (U.S.), through the Medical Heritage Library. The original may be consulted at the National Library of Medicine (U.S.)
148/504
![is insoluble in water; with the aid of heat it is completely dissolved by muriatic acid with the disengagement of sulphuretted-hydrogen gas. Adulterations.—Although not liable to adulteration, as met with in commerce it contains many impurities ; most of these are detected by dissolving in muriatic acid ; hut there is one of much importance which this test will not detect, and which is seldom wanting, namely, arsenic ; its presence may be shown by the reduction test as before described for arsenic, the (page 116,) sulphuret having been previous- ly mixed with charcoal and carbonate of soda. Therapeutical Effects.—This preparation is at present not used in medicine, it was formerly administered as a diaphoretic in doses of from gr. x. to 3ij-> in cutaneous and scrofulous diseases, and in gout and rheumatism. It is employed in pharmacy for preparing the other antimonial compounds. Antimonii sulphuretum aureum, E. Suphur antimoniatum fus- cum, D. Antimonii oxysulphuretum, L.—[Antimonii sulphuretum precipitatum, U. S.]—Golden sulphuret of antimony ; Oxijsulphuret of antimony. Preparation.—Dub-—Prepared sulphuret of antimony, lpart; water of caustic potash, 18 parts ; dilute sulphuric acid, 11 parts or a sufficiency; add the sulphuret to the water of caustic potash, and boil for an hour ; filter the warm liquor through doubled linen, and drop it into the dilute sulphuric acid; wash away the sulphate of potash with warm] water ; dry the golden sulphuret and reduce to a fine powder. Land.— Sesquisulphuret of anti- mony, powdered, §vij.; solution of potash, Oiv. ; distilled water, cong. ij.; dilute sulphuric acid, a sufficiency; mix the sesquisulphuret of antimony, solution of potash and water together; and boil with a slow fire for two hours, frequently stirring, distilled water being often added, that it may fill about the same measure; strain the liquor, and gradually drop into it as much diluted sulphuric acid, as may be sufficient to throw down the oxy- sulphuret of antimony ; then wash away the sulphate of potash with water, and dry what remains with a gentle heat. Edm.— Sulphuret of antimo- ny, in fine powder, gi.; solution of potash, f§xj.; water, Oij.; mix the water and solution of potash, add the sulphuret, boil for an hour, filter im- mediaiely, and precipitate the liquid while hot, with an excess of diluted sulphuric acid; collect the precipitate on a calico filter, wash it thoroughly with water, and dry it with a gentle heat. Physical Properties.—A light powder of a bright orange colour, odourless and tasteless when pure. Chemical Properties.—Its chemical composition has not been ac- curately ascertained ; in the Edinburgh Pharmacopoeia it is stated to be a mixture or compound of sesquisulphuret of antimony, sesquioxide of antimony, and sulphur. It is permanent in the air, heated in close vessels, sulphur is sublimed ; but if heated in contact with air it burns with a greenish blue flame, evolving sulphurous acid and leaving a greyish residuum. It is insoluble in water, and only partially soluble in dilute acids ; with the aid of heat it is nearly all dissolved by solu- tions of the alkalies. Adulterations.—This preparation often contains oxide of iron and sulphur, and is frequently coloured with Brazil-wood or red saunders- wood : all these impurities are readily detected by the tests of the Edinburgh College : twelve times its weight of pure muriatic acid,](https://iiif.wellcomecollection.org/image/b21143602_0148.jp2/full/800%2C/0/default.jpg)
