Microphthalmos with cystic protrusion from the globe / by E. Treacher Collins.

  • Collins, E. Treacher (Edward Treacher), 1862-1937
Date:
[1897]
Catalogue details

Licence: Public Domain Mark

Credit: Microphthalmos with cystic protrusion from the globe / by E. Treacher Collins. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

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    the inner surface of the choroid are frequently seen nodules of hyaline substance lying amongst the pigment epithelial cells (Case 2, 'Trans. Ophth. Soc./ vol. xiii), and also sometimes a formation of bone (Rolston's case). Hyaline nodules of a similar character are also sometimes met with in the retinal tissue in the interior of the cystic protrusions where no choroid is present (Case 2, f Trans. Ophth. Soc./ vol. xiii; Rolston's case; Hess [7] ). In my former communication on this subject to this Society, I referred to the various theories which have been put forward to explain these protrusions of retinal tissue through gaps in the other tunics of the globe. I need not repeat them here, but content myself with the following statement. In all the specimens which I have examined the changes are best explained by considering the inner layer of the secondary optic vesicle to have become unusually rucked and folded, due to some imperfect development of the vitreous humour or delayed closure of the cleft ; that, as the result of this rucking and folding, a portion of the inner layer of the secondary optic vesicle has be- come extruded through the foetal ocular cleft into the sub- jacent mesoblast, where in some cases it has subsequently become expanded into one or more fluid-containing cysts. Case 1 (Clinical notes by Mr. Fischer, House Surgeon). —William M—, aat. 28, admitted to Moorfields Hospital August lObh, 1896. Patient stated that his right eye had been small and shrunken since birth. A doctor who examined it on the third day after birth said it was blind. The condition whs attributed to a fright his mother received while pregnant. Recently it has been very painful, the pain coming on in recurrent attacks, and at times the sight of his left eye getting misty. The right globe was small, and almost completely hidden by overlapping conjunctiva. The left eye was perfectly healthy, and V. = ^. The patient presented no other congenital abnormality.