Contributions to the biochemistry of growth : distribution of nitrogenous substances in tumour and somatic tissues / by W. Cramer and Harold Pringle ; [communicated by E.A. Schäfer].
- Cramer, William, 1878-
- Date:
- 1910
Licence: In copyright
Credit: Contributions to the biochemistry of growth : distribution of nitrogenous substances in tumour and somatic tissues / by W. Cramer and Harold Pringle ; [communicated by E.A. Schäfer]. Source: Wellcome Collection.
Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.
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![[Reprinted from the Proceedings of the Royal SociExy B. Vol 82] Contributions to the Biochemistry of Groivth*—Distribution of Nitrogenous Substances in Tumour and Somatic Tissues. By W. Cramer and Harold Pringle. (Communicated by Prof. E. A. Schafer, F.R.S. Keceived February 3,— Bead February 24, 1910.) (From the Physiology Department, Univei’sity of Edinburgh, and the Imperial Cancer Eesearch Fund, London.) In the preceding paperf a determination of the distribution of the nitrogen retained during a metabolism experiment showed that less nitrogen is needed to build up a given weight of tumour tissue than is necessary to build up an equal weight of the somatic tissues of the host. If this result is correct, it would follow that cancerous tissue should have a lower nitrogen percentage than the somatic tissues of the host. We have therefore carried out nitrogen estimations of various tissues of Kats I, II, and III used in the experiments described in the preceding paper. In order to make our results applicable to carcinomatous tumours, we examined the tissues of mice of about the same age, bearing a rapidly growing * This research is in continuation of papers in ‘ Roy. Soc. Proc.,’ B, vol. 80, 1908, p. 263, and this vol., p. 307, supra. t W. Cramer and Harold Pringle ‘Roy. Soc. Pi’oc.,’ supra, p, 307. b](https://iiif.wellcomecollection.org/image/b22425950_0005.jp2/full/800%2C/0/default.jpg)
