A lipoclastic accelerating action of serum as an index in pathological conditions / by J.A. Shaw-Mackenzie and O. Rosenheim.

  • Shaw-Mackenzie, John A. (John Alexander), 1857-1933.
Date:
1910
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Licence: In copyright

Credit: A lipoclastic accelerating action of serum as an index in pathological conditions / by J.A. Shaw-Mackenzie and O. Rosenheim. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    increased to 8 ; and when 0'5 c.c. serum was added, it rose to 9'7. Or in tabular form :— Table I—Average Normal Serum. N c.c. ^ KOH Acceleration Pancreatic extract alone 5-3 , — Addition of serum, 0-l c.c. ... 7-4 + 2-1 „ 0-25 c.c. ... 8-0 + 2-7 ii u 0-5 c.c. ... 9-7 + 4-4 The following tables summarise our results when we investigated in a similar way the action of serum and serous effusions from pathological cases. Table II gives results with serum from cases of carcinoma, Table III those with serum from non-malignant cases, Table IV those with serous effusions in carcinomatous and non-malignant cases. The first of these was oedema fluid from the arm, and the remainder ascitic fluids. In these cases the amount of fluid available was larger than with serum, and the figures are proportionately higher. Table II—Serum in Carcinoma. Case Recurrent carcinoma; breast Carcinoma of rectum ... Carcinoma of stomach ... Recurrent carcinoma; breast Recurrence of carcinoma of neck Serum added Acceleration 0-25 c.c. + 13-7 (0*25 c.c. + 7*5 0‘5 c.c. + 11-8 0 25 c.c. + 4-9 0’5 c.c. + 10-6 (0-25 c c. + 5-2 i 0*5 c.c. + 9-2 0’07 c.c. + 7-2 Table III—Serum in Non-Malignant Disease. Case Syphilis, under treatment, one year Glycosuria Tabes ... ... ... Serum added (0'25 c.c. ]0-5 c.c. 10*1 c.c. •] 0'25 c.c. (0*5 c.c. 0-5 c.c. Acceleration + 4-6 + 5-9 + 5-6 + 8-1 + 10 6 + 16-2 Table IV—Serous Effusions (Carcinoma and Non-Malignant). Case CEdema of arm, secondary to recurrent of breast Ovarian, malignant tumour Peritoneal carcinoma ... Ovarian, malignant tumour Cirrhosis, liver (non-malignant) Cirrhosis of liver ? (non-malignant) Fluid added Acceleration carcinoma 2-5 c.c. + 12-3 2 5 c.c. + 33-0 5-0 c.c. + 27-3 5-0 c.c. + 26-8 5-0 c.c. + 34-1 5-0 c.c. + 20-1