Reactions : a selection of organic chemical preparations important to pharmacy in regard to their behavior to commonly used reagents / by F.A. Flückiger ; translated, rev. and enl. by J.B. Nagelvoort.
- Friedrich August Flückiger
- Date:
- 1893
Licence: Public Domain Mark
Credit: Reactions : a selection of organic chemical preparations important to pharmacy in regard to their behavior to commonly used reagents / by F.A. Flückiger ; translated, rev. and enl. by J.B. Nagelvoort. Source: Wellcome Collection.
166/192 page 138
![Strychnin.—Strychnin Nitrate. Strychnin can be detected plainly with Reagent 23 in an evapo- ration residue of fluid extract Sem. Strychni when very dilute— imperfectly, with Reagent 22. Evaporate one (1) c. c. of fluid ex- tract Sem. Strychni to dryness; add two (2) c. c. water to tho residue; stir with a glass rod; Alter; dilute filtrate with an equal Proportion of water; divide a few drops over a large surface in evaporating dishes, or on porcelain lids; evaporate to dryness and add to one residue with a glass rod, one drop of Reagent 22, to another of Reagent 23. A blue-violet reaction, immediately dis- appearing, takes place; usually brucin and Strychnin are present ]n about equal proportions, varying somewhat. Or add two (2) drops of the Altrate to one (1) c. c. of Reagent 23, contained in a narrow tube, and shake. The Strychnin reaction does not appear, when Strychnin or a Strychnin salt dissolved in glycerol (1:300) is used in testing with sulfuric acid containing chromic acid (Reagent 22). Reagent 23 and cerous hydroxid show the presence of Strychnin; Reagent 23 by the blue violet color, the cerous hydroxid by a fairly permanent pink color, when it is stirred into the glycerol-strychnin solution, to which previously an equal part of sulfuric acid, Reagent 21, has been added. Stryclmin Nitrate. C21 h22 N2 O2 . NO3 H . Ignites when heated to 140°. It is soluble in water and in alco- hol of 94 per cent., 1:90, at 15°. A saturated, watery solution of the salt does not act upon litmus. (a) Reagents 6, 12, 13, 14, 16, 17, 18 and 24 give precipitates with it. The precipitate caused by Reagent 24 is soluble in an excess thereof. The precipitate from Reagent 17 is crystalline; dissolved in sulfuric acid, it gives the blue-violet characteristic Strychnin reaction; the same can be said regarding the precipitate obtained by Reagent 16; it gives a Strychnin reaction, when a solution of it is brought in contact with Reagent 22.—Compare Flückiger, Pharm. Chemie, II., page 517. (b) A red colored fluid is obtained when Strychnin nitrate or a](https://iiif.wellcomecollection.org/image/b28107007_0166.jp2/full/800%2C/0/default.jpg)
