The constituents of olive leaves / by Frederick B. Power and Frank Tutin.
- Frederick Belding Power
- Date:
- [1908?]
Licence: In copyright
Credit: The constituents of olive leaves / by Frederick B. Power and Frank Tutin. Source: Wellcome Collection.
16/18 page 904
![(m. p. 217°), together with tannic matter, brown, amorphous products, and an amount of <i-mannitol equivalent to about 3’4 per cent, of the weight of the air-dried leaves. The portion of the alcoholic extract which was dissolved by boiling water, but separated on cooling, consisted of amorphous resins. The material insoluble in water contained, together with chlorophyll and some resinous matter, small amounts of the hydrocarbons hentri- acontane, C31H64 (m. p. 68—69°), and pentatriaeoutane, C35H72 (m. p. 74-5°), a little of a mixture of fatty acids, and a new mono- carboxylic acid, C22H45'C02H (m. p. 68—69°). In addition to these, it yielded three new crystalline alcohols, which appear to be related to the phytosterols, namely, oleasterol, C20H34O (m. p. 174°), which crystallises in tufts of colourless needles; olestranol, C2rH4202 (m. p. 217—218°), and homo-olestranol, C27I14602 (m. p. 210°; [a]D +71°). The two last-mentioned alcohols crystallise in hard, wart-like masses, and appear to be hydroxyphytosterols. Furthermore, a ijew colourless, crystalline substance, oleanol, C31H480(0H)2,H20 m. p. 303—304°; [a]o + 78*3°), was obtained in an amount equivalent to nearly 3*4 per cent, of the weight of the air-dried leaves. Oleanol contains two hydroxyl groups, one of which possesses phenolic properties. When treated with sodium etlioxide and methyl iodide, it yields a monomethyloleanol, C81H480(0H),0*CH3 (m. p. 194—195°), and this, on acetylation, gives acetylmethyloleanol, C31H4802(0-0Hs)-C0-CHs j (m. p. 215*5°). Diacetyloleanol, 031H4803(C0*CH3)2, fuses at about 208°, and suffers a change which is accompanied by the evolution of gas and the formation of a crystalline substance, C31H4803, which does not melt at 310°. Monoacetyloleanol, C31H4SO2(OH)*CO*0H3 (m. p. 258°), was prepared by heating the diacetyl derivative with aqueous alcohol. The Wellcome Chemical Research Laboratories, London, E.C. R. CLAY AND SONS. LTD. , BREAD ST. HILI E.C, AND BUNGAY SUFFOLK](https://iiif.wellcomecollection.org/image/b30613152_0016.jp2/full/800%2C/0/default.jpg)
